Gestational age at birth is a potentially important modifiable risk factor in neonates with congenital heart disease. We evaluated the relationship between gestational age and outcomes in a multicenter cohort of neonates undergoing cardiac surgery, focusing on those born at early term (ie, 37-38 weeks' gestation). Neonates in the Society of Thoracic Surgeons Congenital Heart Surgery Database who underwent cardiac surgery between 2010 and 2011 were included. Multivariable logistic regression was used to evaluate the association of gestational age at birth with in-hospital mortality, postoperative length of stay, and complications, adjusting for other important patient characteristics. Of 4784 included neonates (92 hospitals), 48% were born before 39 weeks' gestation, including 31% at 37 to 38 weeks. Compared with a 39.5-week gestational age reference level, birth at 37 weeks' gestational age was associated with higher in-hospital mortality, with an adjusted odds ratio (95% confidence interval) of 1.34 (1.05-1.71; P=0.02). Complication rates were higher and postoperative length of stay was significantly prolonged for those born at 37 and 38 weeks' gestation (adjusted P<0.01 for all). Late-preterm births (34-36 weeks' gestation) a...Continue Reading
Results of 102 cases of complete repair of congenital heart defects in patients weighing 700 to 2500 grams
Cardiac surgery in infants with low birth weight is associated with increased mortality: analysis of the Society of Thoracic Surgeons Congenital Heart Database
Prenatal diagnosis and risk factors for preoperative death in neonates with single right ventricle and systemic outflow obstruction: screening data from the Pediatric Heart Network Single Ventricle Reconstruction Trial(∗)
Congenital heart disease infant death rates decrease as gestational age advances from 34 to 40 weeks
Very low-birth-weight infants with congenital cardiac lesions: is there merit in delaying intervention to permit growth and maturation?
Younger gestational age is associated with worse neurodevelopmental outcomes after cardiac surgery in infancy
An empirically based tool for analyzing morbidity associated with operations for congenital heart disease
Contemporary patterns of surgery and outcomes for aortic coarctation: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery Database
Trends in resource utilization associated with the inpatient treatment of neonatal congenital heart disease
The science of assessing the outcomes and improving the quality of the congenital and paediatric cardiac care
Introduction to the STS National Database Series: Outcomes Analysis, Quality Improvement, and Patient Safety
Timing is even more important than we thought! The effect of gestational age versus body weight on outcomes of neonatal heart surgery
Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect
Outcomes of neonates requiring prolonged stay in the intensive care unit after surgical repair of congenital heart disease
Persistent Pulmonary Hypertension of the Newborn with D-transposition of the Great Arteries: Management and Prognosis
Early-Term Birth in Single-Ventricle Congenital Heart Disease After the Fontan Procedure: Neurodevelopmental and Psychiatric Outcomes
Preoperative and Intraoperative Predictive Factors of Immediate Extubation After Neonatal Cardiac Surgery
Cardiovascular profile score as a predictor of acute intrapartum non-reassuring fetal status in infants with congenital heart defects
Late-Term Gestation Is Associated With Improved Survival in Neonates With Congenital Heart Disease Following Postoperative Extracorporeal Life Support
Does Birth at Early-Term Gestation Increase Mortality for Neonates on Extracorporeal Life Support After Cardiac Surgery?
Procalcitonin Is a Better Biomarker than C-Reactive Protein in Newborns Undergoing Cardiac Surgery: The PROKINECA Study
The impact of the maternal-foetal environment on outcomes of surgery for congenital heart disease in neonates
Best on time, not a little early: gestational age and outcomes for neonates with congenital heart disease
Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery
Hippocampal alterations and functional correlates in adolescents and young adults with congenital heart disease
Preoperative Stabilization of Infants With Hypoplastic Left Heart Syndrome Before Stage I Palliation
Gestational Age and Risk of Mortality in Term-Born Critically Ill Neonates Admitted to PICUs in Australia and New Zealand
Guidelines for the management of neonates and infants with hypoplastic left heart syndrome: The European Association for Cardio-Thoracic Surgery (EACTS) and the Association for European Paediatric and Congenital Cardiology (AEPC) Hypoplastic Left Heart Syndrome Guidelines Task Force.
Factors That Contribute to Cost Differences Based on ICU of Admission in Neonates Undergoing Congenital Heart Surgery: A Novel Decomposition Analysis.
Hemoglobin Level at Stage 1 Discharge has No Impact on Inter-stage Growth and Stability in Single Ventricle Infants
Neonatal and Paediatric Heart and Renal Outcomes Network: design of a multi-centre retrospective cohort study
The Risks of Being Tiny: The Added Risk of Low Weight for Neonates Undergoing Congenital Heart Surgery
Timing and Mode of Delivery in Prenatally Diagnosed Congenital Heart Disease- an Analysis of Practices within the University of California Fetal Consortium (UCfC)
Impaired Fetal Environment and Gestational Age: What Is Driving Mortality in Neonates With Critical Congenital Heart Disease?
Analysis of factors associated with prolonged post-operative course after surgical repair of aortic coarctation.
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Hyperlactataemia as a predictor of adverse outcomes post-cardiac surgery in neonates with congenital heart disease.
Outcomes of Preterm Infants With Congenital Heart Defects After Early Surgery: Defining Risk Factors at Different Time Points During Hospitalization.
Association between Z-score for birth weight and postoperative outcomes in neonates and infants with congenital heart disease.
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Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.