Gestational nanomaterial exposures: microvascular implications during pregnancy, fetal development and adulthood

The Journal of Physiology
Phoebe A Stapleton

Abstract

Air pollution particulate matter and engineered nanomaterials are encompassed in the broad definition of xenobiotic particles. While the effects of perinatal air pollution exposure have been investigated, elucidation of outcomes associated with nanomaterial exposure, the focus of this review, is still in its infancy. As the potential uses of nanomaterials, and therefore exposures, increase exponentially so does the need for thorough evaluation. Up to this point, the majority of research in the field of cardiovascular nanotoxicology has focused on the coronary and vascular reactions to pulmonary exposures in young adult, healthy, male models; however, as intentional and unintentional contacts persist, the non-pulmonary risks to under-represented populations become a critical concern. Development of the maternal-fetal circulation during successful mammalian gestation is one of the most unusual complex, dynamic, and acutely demanding physiological systems. Fetal development in a hostile gestational environment can lead to systemic alterations, which may encourage adult disease. Therefore, the purpose of this review is to highlight the few knowns associated with gestational engineered nanomaterial exposure segmented by physiologica...Continue Reading

References

Feb 1, 1992·Journal of Epidemiology and Community Health·D J Barker, C N Martyn
Nov 1, 1991·British Journal of Obstetrics and Gynaecology·J G Thorpe-BeestonS Campbell
Nov 17, 1990·BMJ : British Medical Journal·D J Barker
Feb 1, 1987·Proceedings of the Society for Experimental Biology and Medicine·L JovanovicJ Aarons
Feb 13, 2001·Acta Obstetricia Et Gynecologica Scandinavica·H J SinghA Nila
Nov 14, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Joey P Granger
Jun 19, 2004·Inhalation Toxicology·G OberdörsterC Cox
Sep 4, 2004·Environmental Health Perspectives·Timothy R NurkiewiczMatthew A Boegehold
Aug 9, 2005·Mutation Research·Lotte RisomSteffen Loft
Oct 8, 2005·Particle and Fibre Toxicology·Günter OberdörsterUNKNOWN ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group
Mar 2, 2006·Environmental Health Perspectives·Timothy R NurkiewiczMatthew A Boegehold
Aug 3, 2006·Environmental Health Perspectives·Alison ElderGünter Oberdörster
Feb 17, 2007·Clinical Obstetrics and Gynecology·Mark Anthony Hill
Apr 24, 2007·Environmental Toxicology and Chemistry·Jinping ChengShuk Han Cheng
May 22, 2007·Clinical Obstetrics and Gynecology·Giancarlo Mari, Farhan Hanif
Jul 28, 2007·American Journal of Respiratory Cell and Molecular Biology·Alexey V FedulovLester Kobzik
Aug 9, 2007·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Georges Boog
Sep 25, 2007·Nature Biotechnology·Hak Soo ChoiJohn V Frangioni
Feb 27, 2008·Toxicology and Applied Pharmacology·Crystal Y UsenkoRobert L Tanguay
Feb 29, 2008·Journal of Toxicology and Environmental Health. Part a·Rhonda D PrisbyTimothy R Nurkiewicz
Aug 2, 2008·Carbon·Crystal Y UsenkoRobert L Tanguay
Dec 5, 2008·Journal of Nanoscience and Nanotechnology·P V AsharaniS Valiyaveettil
Jan 13, 2009·American Journal of Respiratory and Critical Care Medicine·Andrea BaccarelliJoel Schwartz
May 19, 2009·Fertility and Sterility·Seiichi YoshidaTakamichi Ichinose
Aug 11, 2009·Current Opinion in Pediatrics·Andrea Baccarelli, Valentina Bollati
Nov 26, 2009·Journal of Nanoscience and Nanotechnology·Günter OberdörsterAmber Rinderknecht
Feb 25, 2010·Heredity·V Bollati, A Baccarelli
May 12, 2010·Circulation·Robert D BrookUNKNOWN American Heart Association Council on Epidemiology and Prevention, Council on the Kidney in Cardiovascular Disease, and Coun
Jun 16, 2010·Particle and Fibre Toxicology·Karin S HougaardUlla Vogel
Jul 6, 2010·Reproductive Toxicology·Makoto EmaJunko Nakanishi
Aug 17, 2010·Advanced Drug Delivery Reviews·Siti M JanibJ Andrew MacKay
Jan 22, 2011·Birth Defects Research. Part B, Developmental and Reproductive Toxicology·Jeong-Hyeon LimJong-Choon Kim
Jun 28, 2011·Basic & Clinical Pharmacology & Toxicology·Petra JacksonKarin S Hougaard
Sep 29, 2011·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Phoebe A StapletonTimothy R Nurkiewicz
Oct 19, 2011·Toxicology and Applied Pharmacology·Nicola A PhilbrookVirginia K Walker

❮ Previous
Next ❯

Citations

Apr 16, 2016·The Journal of Physiology·Giovanni E Mann
May 20, 2017·Nanomedicine·Yazhou Wang, Guixue Wang
Feb 24, 2018·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Antonio PietroiustiKai Savolainen
Jan 1, 2019·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Jeanine N D'Errico, Phoebe A Stapleton
Jan 13, 2018·Particle and Fibre Toxicology·P A StapletonT R Nurkiewicz
Jan 17, 2020·American Journal of Reproductive Immunology : AJRI·Nicole S OlgunStephen S Leonard
Sep 19, 2019·Nature Communications·Hannelore BovéTim S Nawrot
May 27, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·N'Dea S Irvin-ChoyEmily S Day
Jul 13, 2020·Particle and Fibre Toxicology·Battuja Batbajar DugershawTina Buerki-Thurnherr
Jul 28, 2019·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·J N D'ErricoP A Stapleton
Aug 30, 2021·Advanced Drug Delivery Reviews·Anjali SharmaRangaramanujam M Kannan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Microcirculation : the Official Journal of the Microcirculatory Society, Inc
Phoebe A StapletonTimothy R Nurkiewicz
The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
I Y KhanK H Nicolaides
Expert Review of Obstetrics & Gynecology
Lawrence N Odom, Hugh S Taylor
© 2021 Meta ULC. All rights reserved