Gestational trophoblastic disease among Hispanic women: a 21-year hospital-based study

Gynecologic Oncology
Richard D DrakeJohn O Schorge

Abstract

Hispanics are the fastest growing minority group in the United States. Few reports have described gestational trophoblastic disease (GTD) in this population. The purpose of this study was to determine the incidence of GTD at our public hospital which primarily serves the Hispanic population. All women diagnosed with GTD (partial and complete hydatidiform mole, choriocarcinoma) between 1983 and 2004 were identified from the institutional tumor registry, surgical pathology reports and hospital ICD-9 codes. Clinical data were retrospectively extracted from medical records. The live birth denominator was tabulated over the same interval of time by retrieving labor and delivery statistics and sorting by race. GTD was diagnosed in 596 patients over a 21-year study interval encompassing 289,897 live births. The overall incidence of GTD was 2.06/1000 live births. Hispanic women had a higher incidence compared to Blacks (2.38 vs. 1.34; P < 0.001), but not Whites (2.00; P = 0.17). The 416 Hispanic women were diagnosed with GTD at an earlier gestational age in the latter part of this study (12.3 vs. 16.2 weeks; P < 0.001). Hispanics were more likely to have a partial hydatidiform mole compared to Blacks (29% vs. 13%; P < 0.001) and Whites...Continue Reading

References

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Citations

Jun 28, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Nisrin AnfinanHesham Sait
Jan 21, 2011·Gynecologic Oncology·Charlotte LybolLeon F A G Massuger
Aug 4, 2016·Gynecologic Oncology·Alexander MelamedNeil S Horowitz
Apr 30, 2017·JAAPA : Official Journal of the American Academy of Physician Assistants·Elyse J WatkinsChristina Saldanha
Jan 22, 2009·Obstetrics and Gynecology·Nonna V KolomeyevskayaMatthew L Anderson

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