Getting a Taste for Parasites in the Gut

Immunity
P'ng Loke, Ken Cadwell

Abstract

How type 2 immune responses are initiated is obscure. Nadjsombati et al. (2018), along with two other studies (Lei et al., 2018; Schneider et al., 2018), show that tuft cells can initiate type 2 responses by recognizing the metabolite succinate produced by intestinal parasites.

References

Dec 18, 2015·Nature·Jakob von MoltkeRichard M Locksley
Apr 16, 2016·Science·Deepshika RamananKen Cadwell
Nov 12, 2016·The Journal of Experimental Medicine·Nichole K EscalanteThierry Mallevaey
Sep 5, 2017·Nature·Vânia CardosoHenrique Veiga-Fernandes
May 8, 2018·Proceedings of the National Academy of Sciences of the United States of America·Weiwei LeiPeihua Jiang
Jun 12, 2018·Cell·Christoph SchneiderRichard M Locksley
Jul 19, 2018·Immunity·Marija S NadjsombatiJakob von Moltke

❮ Previous
Next ❯

Citations

May 6, 2020·Nature Reviews. Immunology·William C GauseP'ng Loke
Oct 23, 2019·Signal Transduction and Targeted Therapy·Ziying ZhangYongguang Tao
May 28, 2019·Frontiers in Immunology·Alessandro PoggiMaria Raffaella Zocchi
Jan 25, 2021·The Journal of Allergy and Clinical Immunology·Julia BorowczykWolf-Henning Boehncke
Oct 11, 2020·Signal Transduction and Targeted Therapy·Ziying ZhangYongguang Tao

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Trends in Parasitology
Richard K Grencis, John J Worthington
Endoscopy
Michael Sai Lai Sey, John M DeWitt
Rinsho hoshasen. Clinical radiography
Nature Reviews. Immunology
Kirsty Minton
© 2022 Meta ULC. All rights reserved