Getting greasy: how transmembrane polypeptide segments integrate into the lipid bilayer

Molecular Microbiology
G von Heijne

Abstract

Many integral membrane proteins use the same translocation machinery for membrane insertion as secretory proteins use to get across the membrane. This requires that transmembrane segments can be discriminated from other parts of the protein during membrane translocation, and further requires that the transmembrane segments can be moved laterally out of the translocation channel into the surrounding lipid. The molecular basis for this remarkable intramembraneous sorting event is a major focus of current studies of membrane protein biogenesis.

Citations

Sep 2, 1999·Trends in Microbiology·C WachterM A Schmidt
Aug 10, 2000·Molecular Microbiology·E H Manting, A J Driessen
Apr 10, 1999·Molecular Biology of the Cell·L LecordierM F Cesbron-Delauw
Jan 1, 2011·ISRN Rheumatology·Ihsane HmamouchiNajia Hajjaj-Hassouni
Jun 3, 2011·Trends in Cell Biology·Kush Dalal, Franck Duong
Feb 27, 1999·Current Opinion in Structural Biology·P J Booth, A R Curran
Aug 31, 2010·Biochimica Et Biophysica Acta·David J F du PlessisArnold J M Driessen
Nov 18, 2004·Biochimica Et Biophysica Acta·Sandra J Facey, Andreas Kuhn
Dec 22, 1999·The Journal of Biological Chemistry·M Bogdanov, W Dowhan
Sep 18, 1997·Microbiology and Molecular Biology Reviews : MMBR·L Thöny-Meyer

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