Giant cerebral arterial aneurysm in an infant: report of a case and review of 42 previous cases in infants with cerebral arterial aneurysm

Acta Paediatrica Japonica; Overseas Edition
E KasaharaC Yamane

Abstract

A giant cerebral aneurysm with subarachnoidal hemorrhage in a 4-month-old female infant is reported. The clinical course was complicated by an electrolyte imbalance and unexpected intoxication by phenobarbital. She died as a result of the third episode of rerupture of the aneurysm on the 16th day after onset. Histological findings showed that the aneurysm was of the saccular type, 35 x 20 x 22 mm in size, arising from the basilar artery. The aneurysmal wall consisted microscopically of fibrous tissue with partial absence or fragmentation of the internal elastic lamina and muscular lamina. Forty-three cases of cerebral aneurysms during the first year of life including the present case were summarized and it was found that they could be characterized as follows: (i) a high incidence of onset in early infancy; (ii) larger than 10 mm; (iii) a large number arose from the posterior circulation of the circle of Willis; and (iv) a poor prognosis of non-operated groups, especially in the posterior circulation.

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Citations

Jul 14, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nader SanaiMichael T Lawton
Feb 22, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Javier F CárdenasAdam Kirton
Dec 4, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Osamu MotohashiTakehide Onuma
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Jun 30, 2006·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·D R BuisW P Vandertop
Aug 27, 2014·Journal of Child Neurology·Olcay GüngörCelal Cinar
Jul 22, 1999·The American Journal of Forensic Medicine and Pathology·J Plunkett
Apr 20, 1999·The American Journal of Forensic Medicine and Pathology·J Plunkett
Jul 20, 2021·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Christen M O'NealAhmed A Cheema

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