Abstract
Among nonmelanoma skin cancer (NMSC), basal cell carcinoma (BCC), and squamous cell carcinoma (SCC) are the most common. Giant NMSCs have occasionally reported in the medical literature with particular problems related to diagnosis and treatment. The aim of this study was to analyze patients, treatment, and outcome with giant BCC/SCC. We analyzed our files between January 1, 2008, and December 31, 2011, of an academic teaching hospital in the dermatology department. Patients were analyzed according to demographic factors, clinical presentation, histopathology, treatment, and outcome. American Society of Anesthesiology physical status system was used to assess the fitness of patients before surgery. The frequency of giant NMSC was estimated as 0.4% for both tumor entities. 80% of giant BCC patients were female and 100% of giant SCC patients were male. The mean age was 81.5 ± 8.5 years for BCC) and 79.5 ± 11.4 years for SCC. The major anatomical site was the scalp. Four of 10 BCCs were classified metatypic (basosquamous). Perineural infiltration was seen in 5 NMSCs. Seventy percent of patients had an ASA score ≥3. Surgery was performed in general anaesthesia in 5 (BCC) and 6 (SCC) patients, respectively. All other patients were o...Continue Reading
References
Mar 13, 1998·Southern Medical Journal·W O ThomasR Harrington
Dec 25, 2004·Journal of Cancer Research and Clinical Oncology·Uwe WollinaErich Köstler
Nov 25, 2005·The New England Journal of Medicine·Adam I RubinDésirée Ratner
Aug 3, 2006·The British Journal of Dermatology·B A RaaschC Garbe
Dec 5, 2006·Journal of the American Academy of Dermatology·Cheng-Sheng ChiuYa-Hui Chuang
May 2, 2007·Annals of Plastic Surgery·Phillip L LackeyJ Woodfin Kennedy
Jul 12, 2008·The Lancet Oncology·Kay D BrantschHelmut Breuninger
Sep 26, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Axel HauschildClaus Garbe
Sep 26, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Helmut BreuningerClaus Garbe
Aug 18, 2009·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ali Asilian, Fateme Andalib
Nov 3, 2009·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Adel FattahJonathan A Britto
Mar 26, 2010·The Journal of Investigative Dermatology·Cynthia HolterhuesTamar Nijsten
Jun 10, 2010·International Wound Journal·Uwe Wollina
Apr 1, 2011·International Wound Journal·Uwe WollinaAndreas Weber
Jul 2, 2011·Trials·Nina BadertscherRalph P Braun
Sep 13, 2011·Progress in Biophysics and Molecular Biology·Rüdiger Greinert, Mathieu Boniol
Oct 18, 2011·World Journal of Surgical Oncology·Adel DenewerMohammad Kasem
Jan 4, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·G ZoccaliM Giuliani
Jan 27, 2012·Journal of Cutaneous and Aesthetic Surgery·Uwe Wollina
Citations
Apr 17, 2013·Wiener medizinische Wochenschrift·Uwe Wollina, Georgi Tchernev
Mar 11, 2015·Dermatologic Therapy·Francesco RicciRodolfo Capizzi
Dec 12, 2012·The Journal of Dermatological Treatment·Pier Alessandro FantiAnnalisa Patrizi
Oct 3, 2014·Wiener medizinische Wochenschrift·Georgi TchernevUwe Wollina
Jun 11, 2016·JAAD Case Reports·Brett R BarlowJohn David Wofford
May 13, 2017·Journal of Medical Case Reports·Evangelos P MisiakosAnastasios Machairas
Feb 6, 2016·Annals of Dermatology·Mi So LeeHei Sung Kim
Jul 13, 2013·Wiener medizinische Wochenschrift·Kristina SemkovaUwe Wollina
Sep 4, 2015·The American Journal of Dermatopathology·Fabiola Jiménez-HernándezJosé A Ramos-Garibay
Aug 25, 2020·Avicenna Journal of Medicine·Ahmad KaakoCassidy P Goff
Mar 8, 2020·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·Susanne Darr-FoitSteven Goetze
Jun 15, 2021·Cancer Treatment and Research Communications·Valerie van DamLambert Julien
Aug 12, 2019·International Journal of Surgery Case Reports·P A LópezH Conrado