Giant toxic multinodular goiter with dyspnea: A case report

International Journal of Surgery Case Reports
Sujeethra AlaguvelsamyRamalingam Kombupalayam Komarappa Gounder

Abstract

Toxic multinodular goiter (MNG) involves an enlarged thyroid gland, is a common cause of hyperthyroidism and when it is accompanied by obstructive symptoms such as dyspnea, it carries an indication for surgery. We present a case of 47-year old female with multinodular goiter with a rapid increase in size within 2 years. She also reported palpitation, breathlessness on exertion, tachycardia and hand tremor. Computed tomography scan of the neck shows a gross enlargement of thyroid gland across both sides of the neck. The fine needle aspiration cytology and final histopathological examination were suggestive of MNG with adenomatous nodules and toxic changes respectively. A total thyroidectomy was performed and the gland was dissected successfully. Toxic MNG is most effectively treated by total thyroidectomy, which achieves complete diminution from symptoms. Surgery for huge goiter is challenging and one should be careful about difficult intubation, altered anatomy and adhesions to the surrounding structures. Recognizing and treating this kind of cases are important, as they constitute a preventable cause of mortality if timely diagnosed and treated.

References

Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·M Regina CastroJohn C Morris
Aug 21, 2003·Lancet·David S Cooper
Oct 27, 2005·Surgery Today·Antonio RíosPascual Parrilla
Jun 10, 2006·BMJ : British Medical Journal·Elizabeth N Pearce
May 15, 2007·ANZ Journal of Surgery·Deepak AbrahamChung-Yau Lo
Nov 30, 2010·Hormones : International Journal of Endocrinology and Metabolism·Stavros N KaramanakosKonstantinos Vagenas
Feb 11, 2011·The New England Journal of Medicine·Douglas S Ross
Oct 4, 2011·Indian Journal of Endocrinology and Metabolism·Ambika Gopalakrishnan Unnikrishnan, Usha V Menon
Mar 27, 2012·The Medical Clinics of North America·Geanina Popoveniuc, Jacqueline Jonklaas
Jan 13, 2018·Gland Surgery·Yuk Kwan Chang, Brian H H Lang
Oct 21, 2018·International Journal of Surgery·Riaz A AghaUNKNOWN SCARE Group
Dec 14, 2018·BMC Endocrine Disorders·Erin FanningEmily Mackenzie

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Related Papers

Ryōikibetsu shōkōgun shirīzu
T Okamoto, T Obara
Nederlands tijdschrift voor geneeskunde
W J Fagel, J C van der Vijver
Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte
F C Luft
© 2021 Meta ULC. All rights reserved