Giardia lamblia produces alanine anaerobically but not in the presence of oxygen

Molecular and Biochemical Parasitology
T A PagetD Lloyd

Abstract

Proton nuclear magnetic resonance was used to follow glucose metabolism in Giardia lamblia. Under strictly anaerobic conditions this organism produces equimolar ethanol and alanine as well as CO2 and some acetate. Aerobically the production of both alanine and ethanol are inhibited and more acetate and CO2 are formed. These changes in the balance of products are reversible over the range 0-46 microM O2. In the presence of 46 microM O2, alanine was not detectable. The O2-sensitivity of alanine production may highlight the necessity for redox-balancing reactions in an organism exposed in situ to fluctuating concentrations of O2.

References

Nov 1, 1989·Molecular and Biochemical Parasitology·M R EdwardsW J O'Sullivan
Mar 1, 1985·The Journal of Experimental Medicine·S M AldrittC C Wang
Mar 1, 1980·Molecular and Biochemical Parasitology·D G Lindmark
Feb 1, 1981·Molecular and Biochemical Parasitology·E L JarrollS A Morse
Jan 1, 1982·European Journal of Biochemistry·N E MackenzieA I Scott

❮ Previous
Next ❯

Citations

Feb 1, 1993·International Journal for Parasitology·J E EllisD Lloyd
Jul 1, 1992·Molecular and Biochemical Parasitology·M R EdwardsM Costello
Sep 1, 1993·Molecular and Biochemical Parasitology·M R EdwardsP J Schofield
Jan 1, 1993·Molecular and Biochemical Parasitology·T A PagetD Lloyd
Mar 1, 1994·Molecular and Biochemical Parasitology·T NygaardP J Schofield
Jun 14, 2002·International Journal for Parasitology·Siddhartha DasKrishna Reddy
Mar 21, 1998·International Journal for Parasitology·D M BrownP Upcroft
Apr 23, 2003·Molecular and Biochemical Parasitology·Giancarlo A BiaginiMichael R Edwards
Dec 11, 2003·Parasitology International·Carlos A Niño, Moises Wasserman
Jul 4, 2001·Clinical Microbiology Reviews·R D Adam
Jun 13, 2012·Microbiology and Molecular Biology Reviews : MMBR·Miklós MüllerWilliam F Martin
Jul 1, 2005·The Journal of Parasitology·S M T HassanAntonio Osuna
Feb 13, 2001·Biochemical and Biophysical Research Communications·B Garat, H Musto
Nov 1, 1995·Antonie van Leeuwenhoek·J OrlygssonB H Svensson
Dec 15, 2015·Parasitology·Victoria Morin-Adeline, Jan Šlapeta
Sep 6, 2015·International Journal for Parasitology·Showgy Y Ma'ayehStaffan G Svärd
Aug 13, 2003·Journal of Applied Microbiology·D LloydM R Edwards
Dec 3, 2014·Molecular and Biochemical Parasitology·David Lloyd, Catrin F Williams
Apr 12, 2017·Infection and Immunity·N R BarashS C Dawson
Dec 14, 2016·The Cochrane Database of Systematic Reviews·Germana V GregorioElizabeth G Martinez
Mar 8, 2002·Microbiology·David LloydJanine C Harris
May 11, 2004·Microbiology·Timothy PagetDavid Lloyd
Jun 18, 2017·Frontiers in Cellular and Infection Microbiology·Jonathan K PhamScott C Dawson
Dec 14, 2005·Applied and Environmental Microbiology·G A BiaginiD Lloyd
Aug 12, 2021·Clinical Microbiology Reviews·Rodney D Adam

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Molecular and Biochemical Parasitology
T A PagetD Lloyd
Molecular and Biochemical Parasitology
P J SchofieldJ R Wilson
Molecular and Biochemical Parasitology
M R EdwardsM Costello
© 2021 Meta ULC. All rights reserved