Gitelman's syndrome in pregnancy: case report and review of the literature

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Fergus P McCarthyLouise C Kenny

Abstract

Gitelman's syndrome (GS), a rare renal disorder, results in hypokalaemia, hypomagnesaemia, hypocalciuria and a metabolic alkalosis. It is unclear if an alteration in management is necessary or beneficial during pregnancy. A 32-year-old woman with GS was managed in her second pregnancy. Antenatally, the patient required 39 (principally day case) admissions to the hospital for intravenous (IV) therapy and received a cumulative total of 47 l of IV 0.9% saline solution, 47 doses of 20 mmol magnesium chloride and 46 doses of 80 mmol potassium chloride. She delivered a 2940-g female infant in excellent condition by caesarean section. We would suggest that close attention to maternal weight gain during pregnancy is an easily available clinical tool to assess adequacy of fluid and electrolyte repletion in this condition.

References

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Citations

Oct 18, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Lorenzo A Calò, Paola Caielli
Sep 1, 2016·Case Reports in Medicine·Maria Czarina AcelajadoWilburn D Bolton Iii
Mar 1, 2011·Obstetric Medicine·F RaffiW M Bennet
Apr 11, 2017·Kidney Research and Clinical Practice·Minhyeok LeeSe-Hee Yoon
Mar 15, 2019·Case Reports in Medicine·Muhammad Asim ShahzadMohsin Hamid
Aug 21, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Jingfei ZhangJinghui Tu
Dec 1, 2012·Clinical Kidney Journal·Michael N Moustakakis, Margarita Bockorny
Apr 24, 2021·Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·Stephan RombachMartin Alexander Schick

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