Glaucoma and mortality in the Beijing Eye Study

Eye
L XuJost B Jonas

Abstract

To assess the relationship between glaucoma and mortality in a population-based setting. At baseline in 2001, the Beijing Eye Study examined 4356 subjects for glaucoma with a detected glaucoma frequency of 135/4356 or 3.1%. Mean age was 55.9+/-10.4 years (40-101 years). In 2006, all study participants were reinvited for a follow-up examination. Out of the 4356 subjects, 3208 (73.6%) subjects returned for follow-up examination, while 124 (2.8%) subjects were dead, and 1024 (23.5%) subjects did not agree to be re-examined or had moved away. Mortality rate was significantly (P<0.001; odds ratio (OR): 4.72; 95% confidence interval (CI): 2.67, 8.33) higher in the 135 glaucoma subjects (15/135 or 11.1+/-2.7%; 95% CI: 5.8, 16.4) than in the 4221 participants without glaucoma (109/4221 or 2.6+/-0.2%; 95% CI: 2.2, 3.0). In binary logistic regression analysis, mortality was significantly associated with age (P<0.001), gender (P<0.001; OR: 0.44; 95% CI: 0.29, 0.66), level of education (P<0.001; OR: 0.64; 95% CI: 0.55, 0.74), and the presence of glaucoma (P=0.007; OR: 2.30; 95% CI: 1.26, 4.20). If the whole glaucoma group was differentiated into an open-angle glaucoma group and an angle-closure group, mortality was still significantly asso...Continue Reading

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Citations

Apr 9, 2008·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·A AlwitryS A Vernon
Aug 13, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Xi Wei XieJost B Jonas
Oct 5, 2010·The International Journal of Biochemistry & Cell Biology·G Martinez, R U de Iongh
Feb 7, 2009·Ophthalmology·Liang XuJost J Jonas
May 12, 2009·Acta Ophthalmologica·Jost B JonasYa Xing Wang
Aug 14, 2018·The British Journal of Ophthalmology·Rohit C KhannaGullapalli Nageswara Rao
Feb 26, 2009·Current Opinion in Ophthalmology

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