Glaucoma Drug Therapy in Pregnancy: Literature Review and Teratology Information Service (TIS) Case Series

Current Drug Safety
Marcella PellegrinoMarco De Santis

Abstract

There are many contradictions about pregnancy and fetal/neonatal outcomes after topical use of timolol alone or timolol in combination with other antiglaucoma medications. Seventy-five pregnant women exposed to antiglaucoma medications were followed prospectively by phone interviews. 27 women used timolol as monotherapy, 48 women used timolol as a part of multidrug therapy. We selected a control group of 187 healthy pregnant women. Topical use of timolol alone or timolol in combination with other antiglaucoma medications does not influence pregnancy or fetal/neonatal outcomes. Beta-blocker is the first choice treatment for glaucoma in pregnancy but, when necessary, multidrug therapy should not to be excluded.

Citations

Jul 10, 2019·Journal of Glaucoma·Sunu MathewBrent Siesky
Jan 11, 2020·Current Opinion in Ophthalmology·Bryan Strelow, David Fleischman
Aug 19, 2020·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jack PhuMichael Kalloniatis
Jul 16, 2021·Therapeutic Advances in Ophthalmology·Rashmi KumariAkanchha Kumari
Aug 28, 2021·Diagnostics·Nicoleta AntonIonela Nechita-Dumitriu
Oct 5, 2021·Current Opinion in Ophthalmology·Edmund W C KhongLyndell L Lim

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