Gle1 does double duty

Cell
Ulrike Kutay, Vikram Govind Panse

Abstract

During nuclear export, Gle1 (the nuclear-pore-associated mRNA export factor) activates the DEAD-box protein Dbp5 to remodel exported mRNA-protein complexes on the cytoplasmic face of the nuclear pore complex. In this issue, Bolger et al. (2008) now report additional roles for Gle1 in translation initiation and termination.

References

Feb 3, 2007·Science·Thomas GrossHeike Krebber
Oct 25, 2007·Cell·Andrey V PisarevTatyana V Pestova

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