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Glial Cell Expression of PD-L1

International Journal of Molecular Sciences

Apr 4, 2019

Priyanka Chauhan, James R Lokensgard

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Abstract

The programmed death (PD)-1/PD-L1 pathway is a well-recognized negative immune checkpoint that results in functional inhibition of T-cells. Microglia, the brain-resident immune cells are vital for pathogen detection and initiation of neuroimmune responses. Moreover, microglial cells and...read more

Mentioned in this Paper

Astrocytes
Brain
Malignant Neoplasms
Cessation of Life
Neuroglia
Neuroimmunomodulation
Signal Pathways
Suppression, Genetic
T-Lymphocyte
Up-Regulation (Physiology)
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Glial Cell Expression of PD-L1

International Journal of Molecular Sciences

Apr 4, 2019

Priyanka Chauhan, James R Lokensgard

PMID: 30987269

DOI: 10.3390/ijms20071677

Abstract

The programmed death (PD)-1/PD-L1 pathway is a well-recognized negative immune checkpoint that results in functional inhibition of T-cells. Microglia, the brain-resident immune cells are vital for pathogen detection and initiation of neuroimmune responses. Moreover, microglial cells and...read more

Mentioned in this Paper

Astrocytes
Brain
Malignant Neoplasms
Cessation of Life
Neuroglia

Similar Papers Found In These Feeds

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