PMID: 9181483Feb 1, 1997Paper

Glial organization and chondroitin sulfate proteoglycan expression in the developing thalamus

Journal of Neurocytology
J MitrofanisB E Reese

Abstract

This study examines the early organization of glial cells, together with the expression of chondroitin sulfate proteoglycans in the developing thalamus of ferrets. Glia were identified with antibodies against vimentin and glial fibrillary acidic protein and the chondroitin sulfate proteoglycans were identified by using an antibody against chondroitin sulfate side chains. Our results reveal three striking features of early thalamic development. First, there is a distinct population of glial fibrillary acidic protein-immunoreactive astrocytes (first seen at E30) that resides in the perireticular thalamic nucleus of the primordial internal capsule. These glial fibrillary acidic protein-immunoreactive astrocytes of the perireticular nucleus are transient and form a conspicuous feature of the early developing forebrain. They are first apparent well before any glial fibrillary acidic protein-immunoreactive astrocytes are seen in other regions of the thalamus (at about P8). Further, unlike in other thalamic regions, these peculiar perireticular astrocytes do not express vimentin before they express glial fibrillary acidic protein. Second, in the reticular thalamic nucleus, the radial glial cells express glial fibrillary acidic protein...Continue Reading

Citations

Nov 14, 2000·The Journal of Comparative Neurology·C FrassoniR Spreafico
Aug 24, 2005·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Robin Mihrshahi
Oct 7, 2006·Neuroscience and Behavioral Physiology·D V Nagaeva, A V Akhmadeev
Jul 21, 1999·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·M A Pires NetoR Lent
Feb 9, 2005·The Journal of Comparative Neurology·Roberto LentCathérine Fallet

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