PMID: 8957803Nov 1, 1996Paper

Gliomatosis cerebri presenting with optic nerve involvement: MRI

Neuroradiology
G J FelsbergR McLendon

Abstract

Gliomatosis cerebri is a rare form of astrocytoma characterized by extreme infiltration of the brain structure in conjunction with a relative paucity of clinical findings. We describe the MRI findings in a patient with gliomatosis cerebri widely infiltrating the brain who presented with symptoms related to involvement of the optic nerves and chiasm. Contrast-enhanced MRI showed enlargement of the optic nerves and chiasm with pathological enhancement; T2-weighted images showed extensive infiltration of the brain by tumor. Histopathologic examination of the biopsy specimen showed anaplastic astrocytoma with gemistocytic predominance and a diagnosis of gliomatosis cerebri was reached.

Citations

Jan 24, 2013·Journal of Neuro-oncology·Selby ChenIan F Parney
Jan 7, 2014·Current Treatment Options in Neurology·Roberta RudàMarc Sanson
Jan 21, 2003·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Melissa YipJacques B Lamarche
Jan 5, 2013·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Ilana TraynisMarc Dinkin
Jul 21, 2004·Surgical Neurology·Takashi InoueAkira Ogawa
Oct 12, 2010·Clinical Microbiology Reviews·Sanjay G Revankar, Deanna A Sutton
Oct 4, 2005·Journal of Neuro-oncology·Sophie TaillibertMarc Sanson

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