[Gliosarcoma with multiple extracranial metastases. Case report].

Neurologia Medico-chirurgica
J MatsuyamaA Yamada

Abstract

A 68-year-old male was hospitalized because of headache, nausea, and disturbance of consciousness. Neurological examination on admission disclosed somnolence, disorientation, marked neck stiffness, papilledema, and quadriparesis. Computed tomography (CT) scanning demonstrated a round mass with marked contrast enhancement in the right sylvian fissure and small contrast-enhanced masses in the interpeduncular, quadrigeminal and ambient cisterns. CT also showed marked peritumoral edema, a midline shift, and hydrocephalus. The patient's consciousness level and respiration deteriorated 3 days after admission and a craniotomy was performed. The tumor, which was well demarcated, firmly attached to the sphenoidal ridge, and grossly appeared to be a meningioma, was totally removed. Histologically, the tumor had two well defined components, glioblastoma and fibrosarcoma. The patient underwent ventriculoperitoneal shunting, chemotherapy, and radiotherapy after surgery, but the primary tumor soon recurred, with scalp metastasis, and he died 5 months postoperatively. Autopsy revealed metastases to the liver, spleen, and spinal cord. The histogenesis of this mixed tumor and the mechanism of extracranial metastasis are discussed, and the liter...Continue Reading

Citations

Dec 27, 2011·Cell Biochemistry and Biophysics·LiZhao ChenMinHui Xu
Jul 11, 2003·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·K Ganapathy, Mithra Ghosh
Oct 17, 2003·Neurologia Medico-chirurgica·Takao YasuharaTakashi Ohmoto
May 8, 2010·Neurologia Medico-chirurgica·Daisuke MaedaKatsuji Shima
Jul 17, 2012·Clinical Neurology and Neurosurgery·Richa DawarNikhil I Khushalani
May 20, 2011·British Journal of Neurosurgery·Ahitagni BiswasSuresh Narain Mathuriya
Jun 24, 2017·The Neuroradiology Journal·Luísa SampaioJosé Fonseca
Nov 21, 2017·Journal of Neurosurgical Sciences·Ruichong MaErlick A Pereira
May 14, 2016·Journal of Neuro-oncology·J CastelliG Noel
Jul 19, 2017·CNS Oncology·Gary D LewisBin S Teh
Mar 5, 2008·Journal of Neuro-oncology·Senem DemirciYavuz Anacak
Jun 5, 2018·Fluids and Barriers of the CNS·Bujung HongJoachim K Krauss
Dec 16, 2006·Journal of Neuro-oncology·Thomas L BeaumontAndrew E Sloan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.