Global burden of cancers attributable to infections in 2008: a review and synthetic analysis

The Lancet Oncology
Catherine de MartelMartyn Plummer

Abstract

Infections with certain viruses, bacteria, and parasites have been identified as strong risk factors for specific cancers. An update of their respective contribution to the global burden of cancer is warranted. We considered infectious agents classified as carcinogenic to humans by the International Agency for Research on Cancer. We calculated their population attributable fraction worldwide and in eight geographical regions, using statistics on estimated cancer incidence in 2008. When associations were very strong, calculations were based on the prevalence of infection in cancer cases rather than in the general population. Estimates of infection prevalence and relative risk were extracted from published data. Of the 12·7 million new cancer cases that occurred in 2008, the population attributable fraction (PAF) for infectious agents was 16·1%, meaning that around 2 million new cancer cases were attributable to infections. This fraction was higher in less developed countries (22·9%) than in more developed countries (7·4%), and varied from 3·3% in Australia and New Zealand to 32·7% in sub-Saharan Africa. Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses were responsible for 1·9 million cases, mainly gastr...Continue Reading

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References

Feb 10, 1998·International Journal of Cancer. Journal International Du Cancer·F DonatoM Puoti
Nov 23, 2006·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Luigino Dal Maso, Silvia Franceschi
Dec 31, 2008·International Journal of Cancer. Journal International Du Cancer·Hugo De VuystSilvia Franceschi

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Citations

Feb 14, 2013·JAMA : the Journal of the American Medical Association·Douglas R MorganLaurence H Baker
Dec 25, 2012·Cancer Causes & Control : CCC·Ricardo L DominguezDouglas R Morgan
Oct 12, 2012·Current Gastroenterology Reports·Abhishek Bhandari, Sheila E Crowe
Oct 9, 2013·Current Oncology Reports·Jin Young ParkRolando Herrero
Aug 13, 2013·Clinics and Research in Hepatology and Gastroenterology·Stéphane Chevaliez
Aug 3, 2013·Trends in Microbiology·Marc Lecuit, Marc Eloit
Oct 26, 2013·Trends in Microbiology·Laura K Greenfield, Nicola L Jones
Mar 20, 2013·Chemical Research in Toxicology·Erin G PrestwichPeter C Dedon
Aug 31, 2012·Nature·Margaret Stanley
Nov 10, 2013·Nature Medicine·Daniela F Quail, Johanna A Joyce
Mar 27, 2013·Nature Reviews. Clinical Oncology·Lois B TravisAndrea K Ng
Mar 26, 2013·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P BertuccioC La Vecchia
Jul 12, 2012·Journal of the National Cancer Institute·Christopher Paul Wild
Mar 19, 2013·Journal of the National Cancer Institute·Devasena AnantharamanPaul Brennan
Dec 22, 2012·Infectious Agents and Cancer·Silvia de Sanjosé
Apr 6, 2013·Infectious Agents and Cancer·Dolores Utrera-BarillasMartha-Eugenia Ruiz-Tachiquin
Nov 6, 2013·Infectious Agents and Cancer·Cory Ann LeonardJames Russell Hayman
Jul 25, 2014·PLoS Neglected Tropical Diseases·Peter J HotezMohsen Naghavi
Dec 5, 2012·Endocrine-related Cancer·Sefirin DjioguePaul Faustin Seke Etet
Jul 20, 2013·American Journal of Public Health·Gypsyamber D'SouzaNoel T Brewer
Sep 26, 2013·Toxins·Katharina F KubatzkyDagmar Hildebrand
Apr 8, 2014·Database : the Journal of Biological Databases and Curation·Guang Lan ZhangVladimir Brusic
Feb 18, 2014·Current Obstetrics and Gynecology Reports·Jayne KnoffT-C Wu
Apr 27, 2013·Lancet·Emma J CrosbieHenry C Kitchener
May 1, 2013·The Lancet Oncology·Paul E GossGustavo Azenha
Mar 13, 2014·Nature Reviews. Clinical Oncology·Antonino CarboneSilvia Franceschi
Dec 3, 2013·Cancer Causes & Control : CCC·Suresh H MoolgavkarEdmund C Lau

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