Global distribution of nearly identical phage-encoded DNA sequences

FEMS Microbiology Letters
Mya BreitbartForest Rohwer

Abstract

Phages, the most abundant biological entities on the planet, play important roles in biogeochemical cycling, horizontal gene transfer, and defining microbial community composition. However, very little is known about phage diversity or biogeography, and there has not yet been a systematic effort to compare the phages found in different ecosystems. Here, we report that T7-like Podophage DNA polymerase sequences occur in every major biome investigated, including marine, freshwater, sediment, terrestrial, extreme, and metazoan-associated. The majority of these sequences belong to a unique clade that is only distantly related to cultured isolates. Some identical T7-like phage-encoded DNA polymerase genes from this clade were >99% conserved at the nucleotide level in multiple different environments, suggesting that these phages are moving between biomes in recent evolutionary time and that the global genomic pool for T7-like phages may be smaller than previously hypothesized.

Citations

Jun 7, 2005·Trends in Microbiology·Mya Breitbart, Forest Rohwer
Dec 3, 2010·The ISME Journal·Kimberly P TuckerMya Breitbart
Sep 16, 2005·Nature·Curtis A Suttle
Aug 7, 2012·Nature Reviews. Microbiology·Alejandro ReyesJeffrey I Gordon
Dec 21, 2005·Proceedings of the National Academy of Sciences of the United States of America·Olin K SilanderLin Chao
Jun 25, 2009·Proceedings of the National Academy of Sciences of the United States of America·Ariane BizeDavid Prangishvili
Sep 30, 2010·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·Mahdi BelcaidGuylaine Poisson
Jul 13, 2007·Journal of the Royal Society, Interface·Michael N Dawson, William M Hamner
Sep 11, 2007·Applied and Environmental Microbiology·Noah FiererRobert B Jackson
Oct 9, 2007·Applied and Environmental Microbiology·Shellie R BenchK Eric Wommack
Sep 20, 2011·Applied and Environmental Microbiology·Dawn B GoldsmithMya Breitbart
Oct 7, 2004·Applied and Environmental Microbiology·Emiko SanoForest Rohwer
Jan 11, 2005·Applied and Environmental Microbiology·Cindy M Short, Curtis A Suttle
May 12, 2005·PLoS Biology·Nicholas H Mann
Nov 9, 2006·PLoS Biology·Florent E AnglyForest Rohwer
Dec 19, 2013·PLoS Genetics·Carolina Megumi MizunoRohit Ghai
Sep 30, 2009·PloS One·Appolinaire DjikengDavid J Spiro
Oct 11, 2013·Journal of Virology·James R LaidlerKenneth M Stedman
Aug 3, 2013·Extremophiles : Life Under Extreme Conditions·Christopher M Bellas, Alexandre M Anesio
Mar 14, 2013·Biology & Philosophy·Forest Rohwer, Katie Barott
Oct 9, 2009·Current Opinion in Microbiology·Rebecca Vega Thurber
Sep 4, 2009·Trends in Microbiology·Ramiro LogaresKarin Rengefors
Jul 22, 2008·Research in Microbiology·André M ComeauDavid Prangishvili
Jun 17, 2008·Current Opinion in Microbiology·Michael J Allen, William H Wilson
Jun 21, 2008·Research in Microbiology·Sharath SrinivasiahK Eric Wommack
Jun 14, 2008·Research in Microbiology·Sherwood R Casjens
Jun 24, 2008·Research in Microbiology·Ruth-Anne Sandaa
Feb 15, 2011·International Journal of Microbiology·Veronica CasasStanley R Maloy
Nov 3, 2009·Environmental Microbiology·Forest RohwerDebbie Lindell
Feb 7, 2009·Environmental Microbiology·Nicole L Held, Rachel J Whitaker
Jul 5, 2006·Environmental Microbiology·André M ComeauCurtis A Suttle

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