Get paper from

journal cover

Global Epistasis Makes Adaptation Predictable Despite Sequence-Level Stochasticity

bioRxiv

Jan 13, 2014

Sergey KryazhimskiyMichael M. Desai

Get paper from

Abstract

Epistasis can make adaptation highly unpredictable, rendering evolutionary trajectories contingent on the chance effects of initial mutations. We used experimental evolution in Saccharomyces cerevisiae to quantify this effect, finding dramatic differences in adaptability between 64 clos...read more

Mentioned in this Paper

Saccharomyces cerevisiae allergenic extract
Adaptation
Patterns
Epistasis, Genetic
Clone
Research Study
Saccharomyces cerevisiae
Clone Cells
Genotype Determination
Biological Evolution
9
39
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Global Epistasis Makes Adaptation Predictable Despite Sequence-Level Stochasticity

    bioRxiv

    Jan 13, 2014

    Sergey KryazhimskiyMichael M. Desai

    PMID: 990001784

    DOI: 10.1101/001784

    Abstract

    Epistasis can make adaptation highly unpredictable, rendering evolutionary trajectories contingent on the chance effects of initial mutations. We used experimental evolution in Saccharomyces cerevisiae to quantify this effect, finding dramatic differences in adaptability between 64 clos...read more

    Mentioned in this Paper

    Saccharomyces cerevisiae allergenic extract
    Adaptation
    Patterns
    Epistasis, Genetic
    Clone
    9
    39
    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/global-epistasis-makes-adaptation-predictable/990001784