Global longitudinal strain predicts outcome after MitraClip implantation for secondary mitral regurgitation

Journal of Cardiovascular Medicine
Rodolfo CitroFederico Piscione

Abstract

The aim of this study was to assess preoperative determinants, prevalence, and prognostic impact of left ventricular (LV) reverse remodeling (LVRR) in patients with secondary mitral regurgitation (SMR), undergoing MitraClip implantation (MCi). From March 2012 to January 2015, a total of 41 consecutive patients with moderate-to-severe SMR treated successfully with MCi were enrolled. All patients underwent clinical and echocardiographic follow-up after MCi. Global longitudinal strain (GLS) was obtained using two dimensional speckle tracking analysis. A reduction in LV end-systolic volume more than 10% compared with baseline was considered as a marker of LVRR. Patients were divided into two groups according to the presence or absence of LVRR. Cardiac events were defined as the occurrence of cardiac death, rehospitalization for worsening heart failure, and mitral valve surgery. On univariable analysis, EuroSCORE II and GLS were associated with LVRR. On multivariable logistic regression analysis, GLS was the only independent correlate of LVRR (P = 0.004). A receiver operating characteristic curve identified a cutoff value for GLS of -9.25% (P < 0.001) associated with LVRR, with a sensitivity and specificity of 81 and 74%, respective...Continue Reading

References

Apr 6, 2011·The New England Journal of Medicine·Ted FeldmanUNKNOWN EVEREST II Investigators
May 23, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Sophie MascleErwan Donal
Aug 1, 2012·European Heart Journal Cardiovascular Imaging·Tomasz G WitkowskiNina Ajmone Marsan
Aug 18, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Salvatore ScanduraCorrado Tamburino
Nov 13, 2012·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Eduardo BossoneRobert Naeije
May 2, 2013·Circulation. Cardiovascular Imaging·Elyse FosterUNKNOWN EVEREST Investigators
Jun 5, 2013·European Heart Journal Cardiovascular Imaging·Patrizio LancellottiUNKNOWN Scientific Document Committee of the European Association of Cardiovascular Imaging
Sep 26, 2013·European Heart Journal Cardiovascular Imaging·Nina C Wunderlich, Robert J Siegel
Jan 21, 2014·Journal of Cardiac Failure·Lynn PunnooseEvelyn M Horn
Jan 28, 2014·The Canadian Journal of Cardiology·Robin A DucasJames W Tam
Apr 17, 2014·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Dimosthenis PandisDavid H Adams
Jul 12, 2014·Journal of the American College of Cardiology·Donald D GlowerTed Feldman
Aug 30, 2014·Journal of the American College of Cardiology·Georg NickenigUNKNOWN Transcatheter Valve Treatment Sentinel Registry Investigators of the EURObservational Research Programme of the European Soc
May 16, 2015·The American Journal of Cardiology·Fabrizio D'ascenzoFiorenzo Gaita
Aug 11, 2015·Journal of Cardiovascular Medicine·Salvatore ScanduraCorrado Tamburino
Aug 20, 2016·Journal of Cardiovascular Medicine·Giovanni BenfariCorrado Vassanelli

❮ Previous
Next ❯

Citations

Nov 6, 2018·Journal of Cardiovascular Medicine·Maria S PadulaGiuseppe Boriani
Mar 22, 2019·Anesthesia and Analgesia·Kimberly Howard-QuijanoAman Mahajan
Feb 28, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nicoleta NitaSinisa Markovic
May 21, 2020·ESC Heart Failure·Konstantinos PapadopoulosKonstantinos Spargias
Sep 14, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Roberta De RosaGennaro Galasso
May 7, 2020·European Cardiology·Jaskanwal D SaraNandan S Anavekar
May 16, 2019·The New England Journal of Medicine·Daniel GrinbergBernard Iung
Feb 23, 2020·Journal of the American College of Cardiology·Allan L KleinZoran B Popović
May 16, 2019·The New England Journal of Medicine·Angelo SilverioRodolfo Citro

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiac Remodeling

Cardiac remodeling in response to a myocardial infarction is characterized by progressive ventricular dilatation, cardiac hypertrophy, fibrosis, and deterioration of cardiac performance. Discover the latest research on Cardiac Remodeling here.