Global patterns and trends in colorectal cancer incidence and mortality

Gut
Melina ArnoldFreddie Bray

Abstract

The global burden of colorectal cancer (CRC) is expected to increase by 60% to more than 2.2 million new cases and 1.1 million deaths by 2030. In this study, we aim to describe the recent CRC incidence and mortality patterns and trends linking the findings to the prospects of reducing the burden through cancer prevention and care. Estimates of sex-specific CRC incidence and mortality rates in 2012 were extracted from the GLOBOCAN database. Temporal patterns were assessed for 37 countries using data from Cancer Incidence in Five Continents (CI5) volumes I-X and the WHO mortality database. Trends were assessed via the annual percentage change using joinpoint regression and discussed in relation to human development levels. CRC incidence and mortality rates vary up to 10-fold worldwide, with distinct gradients across human development levels, pointing towards widening disparities and an increasing burden in countries in transition. Generally, CRC incidence and mortality rates are still rising rapidly in many low-income and middle-income countries; stabilising or decreasing trends tend to be seen in highly developed countries where rates remain among the highest in the world. Patterns and trends in CRC incidence and mortality corre...Continue Reading

References

Jan 29, 2000·Statistics in Medicine·H J KimD N Midthune
Aug 17, 2000·JAMA : the Journal of the American Medical Association·C CammàM Cottone
Nov 15, 2000·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·S Kono, Y O Ahn
Dec 18, 2001·British Journal of Cancer·V BagnardiG Corrao
Feb 22, 2002·International Journal of Cancer. Journal International Du Cancer·Teresa NoratElio Riboli
Sep 28, 2002·Mutation Research·Elena Matos, Aldo Brandani
Apr 22, 2004·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·S Kono
Nov 3, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M MalvezziC La Vecchia
Apr 30, 2005·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A K A SamadM A S Chapman
Dec 15, 2005·JAMA : the Journal of the American Medical Association·Yikyung ParkStephanie A Smith-Warner
Jul 4, 2006·The Lancet Oncology·Michael B BartonJesmin Shafiq
Sep 23, 2006·International Journal of Cancer. Journal International Du Cancer·Susanna C Larsson, Alicja Wolk
Nov 11, 2006·International Journal of Cancer. Journal International Du Cancer·Aurélie MoskalElio Riboli
Apr 18, 2007·The American Journal of Gastroenterology·S Elizabeth McGregorAlison Murray
Dec 18, 2008·JAMA : the Journal of the American Medical Association·Edoardo BotteriPatrick Maisonneuve
Jan 15, 2009·International Journal of Cancer. Journal International Du Cancer·Peter S LiangEdward Giovannucci
Feb 12, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·D J HarrissUNKNOWN Colorectal Cancer, Lifestyle, Exercise And Research Group
Apr 2, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Liza N van SteenbergenJan-Willem W Coebergh
Jun 10, 2009·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Melissa M CenterElizabeth Ward
Nov 10, 2009·CA: a Cancer Journal for Clinicians·Melissa M CenterElizabeth Ward
Nov 26, 2009·Gastroenterology·David P TaylorLisa A Cannon-Albright
Dec 4, 2009·British Journal of Cancer·M A Richards
Dec 17, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Liliane ChatenoudCarlo La Vecchia
Mar 27, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·UNKNOWN CanTreat International
May 1, 2010·Lancet·Wendy S AtkinUNKNOWN UK Flexible Sigmoidoscopy Trial Investigators
Feb 11, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V FedirkoM Jenab
Mar 3, 2011·International Journal of Cancer. Journal International Du Cancer·Kueiyu Joshua LinEdward L Giovannucci
Apr 6, 2011·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Cristina BosettiCarlo La Vecchia
Aug 31, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yanlei MaHuanlong Qin
Jan 10, 2012·Nutrition Reviews·Barry M PopkinShu Wen Ng
Feb 1, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Tine JessLaurent Peyrin-Biroulet
Apr 21, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C BosettiC La Vecchia
Nov 22, 2012·Population Health Metrics·Gretchen A StevensUNKNOWN Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index)
Apr 9, 2013·The Lancet Oncology·T Peter KinghamLynette Denny
May 1, 2013·The Lancet Oncology·Paul E GossGustavo Azenha
Nov 15, 2013·Lancet·Hermann BrennerChristian Peter Pox
Apr 3, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V WalterH Brenner
May 1, 2015·Acta Oncologica·Marianne G GurenArne Wibe
Jun 5, 2015·Gut·Eline H SchreudersErnst J Kuipers
Jul 25, 2015·Journal of the National Cancer Institute·Caitlin C MurphyAnn M Geiger

❮ Previous
Next ❯

Citations

Jan 15, 2019·Nutrition and Cancer·Arianna Sasso, Giovanni Latella
Jan 16, 2019·International Journal of Nursing Practice·Merav Ben NatanRana Haj Muhamad
Jan 11, 2019·International Journal of Cancer. Journal International Du Cancer·Chi YanJun Wang
Jan 18, 2019·International Journal of Cancer. Journal International Du Cancer·Susan BengsMichael Scharl
Feb 6, 2019·Virchows Archiv : an International Journal of Pathology·Cleo KeppensElisabeth M C Dequeker
Feb 15, 2019·PloS One·Johannes KloseMartin Schneider
Jan 30, 2019·International Journal of Cancer. Journal International Du Cancer·Roger BlanksJane Green
Feb 10, 2019·International Journal of Cancer. Journal International Du Cancer·Abdo AlnabulsiGraeme I Murray
Feb 6, 2019·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M J GunterS J Chanock
Feb 5, 2019·Journal of Digestive Diseases·Jing Nan Li, Si Yi Yuan
Mar 14, 2019·Cancers·Elisa Conde MorenoCarmen Guillén-Ponce
Mar 22, 2019·Journal of Biochemical and Molecular Toxicology·Jian-Feng YaoXue-Jun Sun
Mar 23, 2019·The Proceedings of the Nutrition Society·S P BreiningerJ C Mathers
Mar 13, 2019·International Journal of Cancer. Journal International Du Cancer·Junyi XinMeilin Wang
Mar 29, 2019·Journal of Cellular Physiology·Shahin AghamiriBabak Negahdari
Mar 5, 2019·International Journal of Cancer. Journal International Du Cancer·Siqi LiZhengping Xu
Apr 6, 2019·Medicinal Research Reviews·Emilio Gil-MartínAlejandro Romero
Apr 13, 2019·Clinical Chemistry and Laboratory Medicine : CCLM·Hanshao LiuXiaoren Zhang
Dec 12, 2018·International Journal of Cancer. Journal International Du Cancer·Marzieh AraghiMelina Arnold
Nov 30, 2016·British Journal of Cancer·Gad Rennert
Mar 6, 2019·Journal of Digestive Diseases·Chung-Kwong YeungBiji Sreedhar
Apr 30, 2019·Artificial Cells, Nanomedicine, and Biotechnology·Yue XieXinying Wang
May 10, 2019·Scientific Reports·Marloes ZoetemelkPatrycja Nowak-Sliwinska
Apr 10, 2019·Medicines·Aravinda Ganapathy, Uthayashanker Ezekiel
May 17, 2019·Journal of Cellular Biochemistry·Sherien M El-DalyAmira M Gamal-Eldeen

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