Global, regional, and country seroprevalence of Toxoplasma gondii in pregnant women: a systematic review, modelling and meta-analysis.

Scientific Reports
Jean Joel BignaJobert Richie Nansseu

Abstract

Efficient health-care for pregnant women require accurate data on the prevalence of toxoplasmosis in pregnancy at global, regional, and country levels. In this systematic review with meta- and modelling-analysis, we searched PubMed, EMBASE, Web of Knowledge, Global Index Medicus, and Africa Journal Online to identify studies that reported enough data to compute the immunoglobulins (Ig) M or G seroprevalence estimates of Toxoplasma gondii in pregnant women up to December 31st, 2018, without any language restriction. The global and regional estimates were done using a random-effects meta-analysis. We included 250 studies with 723,655 pregnant women. The global IgM seroprevalence was 1.9% (95%CI: 1.7-2.3). At the regional level, Eastern Mediterranean had the highest IgM seroprevalence (4.1%, 95%CI: 2.8-5.5) and The Americas, the lowest (1.1%, 0.8-1.4), with a statistically significant difference between WHO regions (p < 0.0001). The global IgG seroprevalence was 32.9% (95%CI: 29.4-36.4). Among WHO regions, The Americas had the highest prevalence (45.2%, 95%CI: 33.4-53.4) and Western Pacific the lowest (11.2%, 7.8-15.1), with a statistically significant difference between regions (p < 0.0001). This study presents a high toxoplasma ...Continue Reading

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Citations

Feb 6, 2021·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Eve RobinsonMathieu Tourdjman
Mar 18, 2021·Revista brasileira de parasitologia veterinária = Brazilian journal of veterinary parasitology : Órgão Oficial do Colégio Brasileiro de Parasitologia Veterinária·Daniella Ferreira Cordeiro GomesCairo Henrique Sousa de Oliveira
Apr 23, 2021·Infection and Drug Resistance·Biyansa AdugnaAbrham Ayele
May 20, 2021·Parasite : Journal De La Société Française De Parasitologie·Tao SunZhaoguo Chen
Jun 23, 2021·Acta Tropica·Fernanda Ferreira EvangelistaAna Lúcia Falavigna-Guilherme
Jun 29, 2021·Frontiers in Psychiatry·Teodor T PostolacheLisa A Brenner
Jul 3, 2021·Pathogens·Carlos FloresZuleima Caballero E
Aug 8, 2021·Parasites & Vectors·Thomas GrochowSimone A Fietz
Aug 9, 2021·Trends in Parasitology·Samuel Cota TeixeiraVeridiana de Melo Rodrigues
Aug 15, 2021·Parasitology Research·Gabriella de Lima BessaErica Dos Santos Martins-Duarte

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