Global, regional, and national burden of brain and other CNS cancer, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016

Lancet Neurology
GBD 2016 Brain and Other CNS Cancer Collaborators

Abstract

Brain and CNS cancers (collectively referred to as CNS cancers) are a source of mortality and morbidity for which diagnosis and treatment require extensive resource allocation and sophisticated diagnostic and therapeutic technology. Previous epidemiological studies are limited to specific geographical regions or time periods, making them difficult to compare on a global scale. In this analysis, we aimed to provide a comparable and comprehensive estimation of the global burden of brain cancer between 1990 and 2016. We report means and 95% uncertainty intervals (UIs) for incidence, mortality, and disability-adjusted life-years (DALYs) estimates for CNS cancers (according to the International Classification of Diseases tenth revision: malignant neoplasm of meninges, malignant neoplasm of brain, and malignant neoplasm of spinal cord, cranial nerves, and other parts of CNS) from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016. Data sources include vital registration and cancer registry data. Mortality was modelled using an ensemble model approach. Incidence was estimated by dividing the final mortality estimates by mortality to incidence ratios. DALYs were estimated by summing years of life lost and years lived ...Continue Reading

Associated Clinical Trials

Citations

Aug 28, 2019·Journal of Alzheimer's Disease : JAD·Maria Skaalum PetersenSofus Joensen
Nov 2, 2019·Nature Communications·Jintai LinKlaus Hubacek
May 19, 2020·Technology in Cancer Research & Treatment·Guangting QiuJiang Zhao
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Methods Mentioned

BETA
biopsy
surgical resection

Software Mentioned

GBD Compare
CODEm
GLOBOCAN
GBD Results Tool

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