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Global reorganisation of cis -regulatory units upon lineage commitment of human embryonic stem cells

ELife

Mar 23, 2017

Paula Freire-PritchettMikhail Spivakov

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Abstract

Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-regulatory elements during lineage comm...read more

Mentioned in this Paper

Gene Expression
Operator gene
Transcriptional Regulation
Early Promoters, Genetic
Enhancer Elements, Genetic
Regulatory Elements, Transcriptional
Genes
Promoter
Embryonic Stem Cells
Regulatory Sequences, Nucleic Acid
73
136
Paper Details
References
    • References86
    • Citations3
    • References86
    • Citations3
  • Global reorganisation of cis -regulatory units upon lineage commitment of human embryonic stem cells

    ELife

    Mar 23, 2017

    Paula Freire-PritchettMikhail Spivakov

    PMID: 28332981

    DOI: 10.7554/elife.21926

    Abstract

    Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-regulatory elements during lineage comm...read more

    Mentioned in this Paper

    Gene Expression
    Operator gene
    Transcriptional Regulation
    Early Promoters, Genetic
    Enhancer Elements, Genetic
    73
    136
    Paper Details
    References
    • References86
    • Citations3
    • References86
    • Citations3
  • Get paper from

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