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Global reorganisation of cis -regulatory units upon lineage commitment of human embryonic stem cells

ELife

Mar 24, 2017

Paula Freire-PritchettMikhail Spivakov

Abstract

Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-regulatory elements during lineage comm...read more

Mentioned in this Paper

Transcriptional Regulation
Pluripotent Stem Cells
Genes
Transcription, Genetic
Promoter
Operator gene
Gene Expression
Cell Differentiation Process
Regulatory Elements, Transcriptional
Drug Interactions
72
144
Paper Details
References
  • References86
  • Citations7

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Global reorganisation of cis -regulatory units upon lineage commitment of human embryonic stem cells

ELife

Mar 24, 2017

Paula Freire-PritchettMikhail Spivakov

PMID: 28332981

DOI: 10.7554/elife.21926

Abstract

Long-range cis-regulatory elements such as enhancers coordinate cell-specific transcriptional programmes by engaging in DNA looping interactions with target promoters. Deciphering the interplay between the promoter connectivity and activity of cis-regulatory elements during lineage comm...read more

Mentioned in this Paper

Transcriptional Regulation
Pluripotent Stem Cells
Genes
Transcription, Genetic
Promoter
Operator gene
Gene Expression
Cell Differentiation Process
Regulatory Elements, Transcriptional
Drug Interactions
72
144

Similar Papers Found In These Feeds

Paper Details
References
  • References86
  • Citations7
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