PMID: 9189964Jan 1, 1997Paper

Global tissue oxygenation during normovolaemic haemodilution in young children

Paediatric Anaesthesia
A Aly HassanK Messmer

Abstract

Sixteen patients (1-8 years) scheduled for major general surgery were chosen for the study. They were divided into two groups according to the replacement solution used for haemodilution (HD); whether 6% middle molecular weight hydroxyethyl starch (HES) or 6% dextran 60 (DEX). After induction of general anaesthesia and pulmonary artery catheterization, a precalculated amount of autologous blood was withdrawn while the patient's autologous blood was simultaneously replaced by either HES or DEX. Autologous blood was retransfused at a minimum haematocrit (Hct.) of 17% or at the end of surgery. The following parameters were measured and/or calculated before and after HD, every 20 min intraoperatively and hourly for 6 h postoperatively: heart rate (HR), mean arterial pressure (MAP), Cardiac index (CI), Hct., arterial and mixed venous oxygen content (CaO2, CvO2) and arterio-venous difference of oxygen content (avDO2), oxygen delivery index (DO2I), oxygen consumption index (VO2I). The cardiovascular system remained stable. There was no significant difference as regards SvO2, despite a significant decrease in CaO2 to 10.8 and 10.0 ml.dl-1 (median values) due to reduction of haemoglobin concentration in the HES and DEX groups respective...Continue Reading

Citations

Apr 13, 2007·Der Urologe. Ausg. A·O HablerB Zwissler
Jun 1, 2005·Anesthesiology Clinics of North America·B Craig Weldon
Oct 29, 2003·Pediatric Neurology·Stephen AshwalLeonard L Bailey
Mar 21, 2000·Transfusion Science·K T Murto, W M Splinter
Apr 22, 2003·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·Miomir-D JovićBosko P Ethukanović
Aug 31, 2002·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Uwe Kreimeier, Konrad Messmer
Jun 1, 2014·Journal of Neurosurgery. Pediatrics·Rafael A VegaJennifer L Rhodes
Apr 15, 2005·Seminars in Pediatric Neurology·C Di RoccoD Pietrini
Sep 19, 2002·American Journal of Therapeutics·Heather A Hume, Pierre Limoges
Jul 2, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jean-Michel LietJean-Christophe Rozé
Oct 22, 2005·Paediatric Anaesthesia·Bogumila Woloszczuk-Gebicka
Mar 26, 2003·European Journal of Anaesthesiology·T P WeberM Booke
Oct 4, 2006·Current Opinion in Anaesthesiology·M Booke, A Reich
Mar 26, 2003·European Journal of Anaesthesiology·M SchywalskyH Schwilden
Mar 26, 2003·European Journal of Anaesthesiology·S G Sakka, A Meier-Hellmann
Jun 18, 2019·The Journal of Craniofacial Surgery·Joshua P KelleyJohn A Girotto
Mar 26, 2003·European Journal of Anaesthesiology·P KrankeN Roewer
Mar 26, 2003·European Journal of Anaesthesiology·J A BlunkW Koppert
Mar 26, 2003·European Journal of Anaesthesiology·P BozkurtM Hacibekiroğlu
Jan 26, 1999·Clinical Orthopaedics and Related Research·R K Spence

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