Global transcriptional profiling of the toxic dinoflagellate Alexandrium fundyense using Massively Parallel Signature Sequencing.

BMC Genomics
Deana L Erdner, Donald M Anderson

Abstract

Dinoflagellates are one of the most important classes of marine and freshwater algae, notable both for their functional diversity and ecological significance. They occur naturally as free-living cells, as endosymbionts of marine invertebrates and are well known for their involvement in "red tides". Dinoflagellates are also notable for their unusual genome content and structure, which suggests that the organization and regulation of dinoflagellate genes may be very different from that of most eukaryotes. To investigate the content and regulation of the dinoflagellate genome, we performed a global analysis of the transcriptome of the toxic dinoflagellate Alexandrium fundyense under nitrate- and phosphate-limited conditions using Massively Parallel Signature Sequencing (MPSS). Data from the two MPSS libraries showed that the number of unique signatures found in A. fundyense cells is similar to that of humans and Arabidopsis thaliana, two eukaryotes that have been extensively analyzed using this method. The general distribution, abundance and expression patterns of the A. fundyense signatures were also quite similar to other eukaryotes, and at least 10% of the A. fundyense signatures were differentially expressed between the two co...Continue Reading

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Citations

Nov 22, 2013·Genome Biology and Evolution·Jennifer H WisecaverJeremiah D Hackett
May 26, 2012·Molecular Biology and Evolution·Jeremiah D HackettDeana L Erdner
May 4, 2010·Applied and Environmental Microbiology·Eve ToulzaDaniel Grzebyk
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Sep 5, 2013·Microorganisms·Martha Valiadi, Debora Iglesias-Rodriguez
Aug 28, 2019·Microorganisms·Yali BiWeiwen Zhang
Feb 9, 2020·Marine Drugs·Muhamad Afiq AkbarHamidun Bunawan
Oct 1, 2010·Environmental Microbiology·Louie L WurchSonya T Dyhrman
Mar 11, 2020·International Journal of Molecular Sciences·Carlos FajardoFrancisco Javier Fernandez-Acero
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Aug 30, 2019·Journal of Proteomics·Carlos FajardoFrancisco Javier Fernandez-Acero
Oct 15, 2020·BMC Biology·Girish BeedesseeEiichi Shoguchi

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Datasets Mentioned

BETA
DY241874-DY241888

Methods Mentioned

BETA
PCR
electrophoresis
EST

Software Mentioned

SAGE
pcp
RACE
Serial Analysis of Gene Expression ( SAGE )
MPSS
GLGI

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