Global transcriptomic analysis of Cyanothece 51142 reveals robust diurnal oscillation of central metabolic processes.

Proceedings of the National Academy of Sciences of the United States of America
Jana StöckelHimadri B Pakrasi

Abstract

Cyanobacteria are photosynthetic organisms and are the only prokaryotes known to have a circadian lifestyle. Unicellular diazotrophic cyanobacteria such as Cyanothece sp. ATCC 51142 produce oxygen and can also fix atmospheric nitrogen, a process exquisitely sensitive to oxygen. To accommodate such antagonistic processes, the intracellular environment of Cyanothece oscillates between aerobic and anaerobic conditions during a day-night cycle. This is accomplished by temporal separation of the two processes: photosynthesis during the day and nitrogen fixation at night. Although previous studies have examined periodic changes in transcript levels for a limited number of genes in Cyanothece and other unicellular diazotrophic cyanobacteria, a comprehensive study of transcriptional activity in a nitrogen-fixing cyanobacterium is necessary to understand the impact of the temporal separation of photosynthesis and nitrogen fixation on global gene regulation and cellular metabolism. We have examined the expression patterns of nearly 5,000 genes in Cyanothece 51142 during two consecutive diurnal periods. Our analysis showed that approximately 30% of these genes exhibited robust oscillating expression profiles. Interestingly, this set inclu...Continue Reading

References

Jul 1, 1990·Trends in Biochemical Sciences·D S MorseJ W Hastings
Jun 15, 1995·Genes & Development·Y LiuT Kondo
Mar 1, 1993·Journal of Bacteriology·K J ReddyL A Sherman
Jun 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·T KondoC H Johnson
Jul 1, 1996·Molecular Microbiology·C H JohnsonT Kondo
Jan 1, 1996·Annual Review of Genetics·C P Wolk
Dec 26, 2001·Nucleic Acids Research·Minoru KanehisaAkihiro Nakaya
Mar 1, 2002·Journal of Microbiological Methods·Setsuyuki AokiMasahiro Ishiura
Aug 17, 2004·The Journal of Biological Chemistry·Johnna L Roose, Himadri B Pakrasi
Aug 25, 2004·Current Biology : CB·Mark A WoelfleCarl Hirschie Johnson
Nov 10, 2004·Journal of Biological Rhythms·Hideo Iwasaki, Takao Kondo
Dec 15, 2004·Proceedings of the National Academy of Sciences of the United States of America·G Dean PriceLoraine Tucker
Mar 4, 2005·Journal of Bacteriology·Ken-ichi KuchoMasahiro Ishiura
Jul 27, 2005·Biochemical Society Transactions·S E HartC J Howe
Feb 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·Anne-Soisig SteunouArthur R Grossman
Oct 4, 2006·Molecular Systems Biology·Andrew C TolonenSallie W Chisholm
Oct 27, 2006·Current Opinion in Microbiology·Jay C Dunlap, Jennifer J Loros
Nov 17, 2006·Journal of Biological Rhythms·Mark A Woelfle, Carl Hirschie Johnson
Feb 1, 2007·Plant, Cell & Environment·Carlos T HottaAlex A R Webb
Jun 28, 2007·Omics : a Journal of Integrative Biology·Rajeev AuroraHimadri B Pakrasi
Sep 7, 2007·Trends in Microbiology·Shannon R Mackey, Susan S Golden
Sep 21, 2007·Nature Reviews. Neuroscience·Erik D Herzog

❮ Previous
Next ❯

Citations

Aug 21, 2013·Photosynthesis Research·Swathi AlagesanPramod P Wangikar
Nov 9, 2011·Journal of Proteome Research·Uma K AryalJon M Jacobs
Jan 27, 2011·Nature Communications·Anindita BandyopadhyayHimadri B Pakrasi
Sep 25, 2008·Proceedings of the National Academy of Sciences of the United States of America·Eric A WelshHimadri B Pakrasi
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Hiroshi ItoHideo Iwasaki
Feb 18, 2010·Proceedings of the National Academy of Sciences of the United States of America·Ertugrul M OzbudakOlivier Pourquié
Jan 21, 2011·Proceedings of the National Academy of Sciences of the United States of America·Mak A SaitoJohn B Waterbury
May 31, 2013·Integrative and Comparative Biology·Markus Friedrich
Mar 28, 2012·Journal of Experimental Botany·Ralf SteuerRainer Machné
Feb 12, 2013·Applied and Environmental Microbiology·Brian P LandryHimadri B Pakrasi
Jun 15, 2012·BMC Bioinformatics·Nguyen Vinh XuanPramod P Wangikar
Feb 13, 2013·BMC Bioinformatics·Nguyen Xuan VinhPramod P Wangikar
May 19, 2009·BMC Genomics·Thanura ElvitigalaHimadri B Pakrasi
Mar 20, 2009·PLoS Biology·Michael Rosbash
Jun 7, 2014·Annual Review of Biochemistry·Carl Hirschie Johnson, Martin Egli
Apr 23, 2014·Proceedings of the National Academy of Sciences of the United States of America·Ryoma TsujimotoYuichi Fujita
Jun 22, 2011·Applied Microbiology and Biotechnology·Naira QuintanaRobert Verpoorte
Jul 11, 2014·Journal of Experimental Botany·Juan J Pierella KarlusichNéstor Carrillo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.