Globulin-p and 11S-globulin from amaranthus Hypochondriacus: are two isoforms of the 11S-globulin.

The Protein Journal
Alejandra V QuirogaM Cristina Añón

Abstract

Amaranth is an ancient crop with a high content of good quality proteins. Globulins are some of the most abundant storage proteins of amaranth grain. They contain two fractions distinguishable according to their different solubility: the salt-soluble 7S and 11S-globulins and the globulin-p soluble in mild-alkaline, low-ionic-strength solutions. As part of the amaranth proteins characterization, in this work we investigated the structural characteristics responsible for the different physicochemical properties of these globulins. We studied certain conformational parameters of the purified aggregates (AMGp) and individual molecules (IMGp) of globulin-p and of the partially purified globulin (ppGb) and compared the AMGp polypeptide sequences with the sequence of the 11S-globulin propolypeptide from Amaranthus (gi|122726601). The results indicated that the AMGp aggregates are responsible for the different solubility of globulin-p. Subtle conformational differences as determined by fluorescence spectroscopy and urea sensitivity were found between the molecules studied: The AMGp showed some surface differences from the IMGp and the ppGb; the AMGp also had a lower affinity for the hydrophobic fluorescent probe 1,8-aniline-naphthalene...Continue Reading

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Citations

Jan 3, 2021·Plant Foods for Human Nutrition·Eliana Isabel Fernández SosaMaría Victoria Avanza
Mar 1, 2015·Comprehensive Reviews in Food Science and Food Safety·Alvaro Montoya-RodríguezElvira González de Mejía
Jan 1, 2017·Comprehensive Reviews in Food Science and Food Safety·Frederik JanssenJan A Delcour
Nov 7, 2020·International Journal of Biological Macromolecules·M C Cortez-TrejoJ D Figueroa-Cárdenas
Dec 2, 2010·Journal of Agricultural and Food Chemistry·Alejandra QuirogaM Cristina Añón

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