PMID: 6105030Jul 1, 1980Paper

Glucagonomas, VIPomas and somatostatinomas

Clinics in Endocrinology and Metabolism
S R Bloom, J M Polak

Abstract

The three new endocrine pancreatic tumour syndromes dealt with in this chapter--glucagonomas, VIPomas and somatostatinomas--are not common. Nonetheless, the patients are potentially curable by tumour resection and therefore wider knowledge of the clinical picture is of considerable importance. It is possible that there are still further, presently unrecognized, clinical syndromes waiting in the wings and studies are currently under way to try to ascertain the effects of elevated PP. Early tumour diagnosis depends firstly on clinical acumen but the easy availability of a reliable radioimmunoassay service is of considerable importance as this allows the physician to screen likely patients and so detect cases at an early stage. Tumour localization is still a major problem and requires expert radiological assistance. The dramatic effectiveness of the cytotoxic agent streptozotocin illustrates the great potential of chemotherapy and it may be expected that further drugs of this nature will be discovered, especially as it is now possible to establish isolated tumour strains for mass drug screening. These tumours have shown the effect of long continued peptide elevation and given valuable insight into the physiological role of the res...Continue Reading

References

Dec 15, 1977·The New England Journal of Medicine·O P Ganda, J S Soeldner
Sep 20, 1979·World Journal of Surgery·S R BloomR B Welbourn
Dec 16, 1978·British Medical Journal·J G KinghamR J Frankel

❮ Previous
Next ❯

Citations

Dec 1, 1992·International Journal of Colorectal Disease·K KusuharaJ Utsunomiya
Mar 1, 1989·Digestive Diseases and Sciences·P N MatonR T Jensen
May 15, 1985·Klinische Wochenschrift·C Weil
Jan 1, 1991·European Journal of Nuclear Medicine·W BeckerF Wolf
Jan 1, 1989·Pharmacology & Therapeutics·D WynickS R Bloom
Mar 1, 1990·Baillière's Clinical Endocrinology and Metabolism·S W LambertsJ C Reubi
May 29, 1987·The American Journal of Medicine·B M Jaffe
Mar 1, 1989·The Veterinary Clinics of North America. Small Animal Practice·M D Willard
Dec 22, 1986·The American Journal of Medicine·T M O'Dorisio
Aug 1, 1987·European Journal of Clinical Investigation·S W LambertsJ C Reubi
Aug 1, 1992·Pharmacology & Toxicology·C MontesissaG Pompa
Jan 1, 1986·Scandinavian Journal of Gastroenterology. Supplement·S L LightmanM J Dunne

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenoma, Islet Cell

Islet Cell Adenoma arises in the islet cells, which are insulin producing cells of the pancreas. These tumors can be either malignant or benign. Discover the latest research on Islet Cell Adenoma here.

Related Papers

Journal of Clinical Pathology. Supplement (Association of Clinical Pathologists)
J F Rehfeld
Clinics in Endocrinology and Metabolism
J J Holst
BMJ : British Medical Journal
N Finlayson
© 2021 Meta ULC. All rights reserved