PMID: 9193219Jun 1, 1997Paper

Glucocorticoid treatment for nasal polyps. The use of topical budesonide powder, intramuscular betamethasone, and surgical treatment

Archives of Otolaryngology--head & Neck Surgery
T LildholdtK Larsen

Abstract

The treatment of nasal polyps is controversial, and medical treatment alone has been little investigated to our knowledge. To examine the efficacy of therapy using only topical budesonide powder and topical budesonide powder supplemented with surgical removal or intramuscular betamethasone. Randomized, double-blind comparison of 2 dosages and additional treatment, if therapy failed. After 1 year, treatment with medication was stopped, and the demand for renewed treatment was monitored for another year. Patients with bilateral nasal polyps who demanded treatment were consecutively enrolled in a hospital outpatient clinic or specialty private practice. During a 15-month period from 1990 to 1992, a total of 126 patients entered the 2-year study. In phase 1, randomized and double-blind treatment with a topical medication, budesonide powder, 800 micrograms or 400 micrograms daily, or a placebo was given for 1 month. In phase 2, randomized and double-blind treatment with budesonide powder, 800 micrograms or 400 micrograms daily, was given. At the end of phase 1, failed therapy was supplemented by randomly assigned treatment of either surgical removal or a single injection of sustained released betamethasone. In phase 3, treatment wit...Continue Reading

Citations

Feb 22, 2014·Current Allergy and Asthma Reports·Christos GeorgalasWytske Fokkens
Sep 24, 2015·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Aydın AcarAdil Eryilmaz
Apr 9, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mehmet PalalıHüseyin Dere
Jul 1, 2005·Women's Health·Eva K Ellegård
Feb 5, 2011·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Aleksandar PericOlivera Miljanovic
Jul 29, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Yuichi KimuraShigeharu Fujieda
Mar 29, 2013·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Mehdi BakhshaeeToktam Moghiman
Oct 3, 2002·Current Allergy and Asthma Reports·Glenis K Scadding
Apr 29, 2010·Current Allergy and Asthma Reports·Marcelo B Antunes, Samuel S Becker
Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Eva K Ellegård
Sep 7, 2007·HNO·B A StuckUNKNOWN German Society for Otorhinolaryngology, Head and Neck Surgery
Dec 6, 2011·HNO·B A StuckUNKNOWN German Society of Otorhinolaryngology, Head and Neck Surgery
Aug 12, 1999·Allergy·M F Kramer, G Rasp
Jan 16, 2014·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Aleksandar PerićOlivera Miljanović
Jul 4, 2009·Expert Review of Medical Devices·Ali S TaghiHesham A Saleh
Feb 3, 2016·International Forum of Allergy & Rhinology·Cveta Špadijer-MirkovićDanilo Vojvodić
Dec 17, 2008·Acta otorrinolaringológica española·Gustavo EisenbergMaría A Moro
May 31, 2011·Otolaryngologic Clinics of North America·Michael A DeMarcantonio, Joseph K Han
Apr 15, 2011·Mayo Clinic Proceedings·Eli O Meltzer, Daniel L Hamilos
Jun 18, 2010·Auris, Nasus, Larynx·Beata Rostkowska-NadolskaUrszula Mazurek
May 11, 2010·The Journal of Allergy and Clinical Immunology·Thibaut Van ZeleClaus Bachert
May 31, 2001·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·R A Settipane, P Lieberman
Mar 31, 2009·Otolaryngologic Clinics of North America·Samuel S Becker
Jan 31, 2006·Immunology and Allergy Clinics of North America·Eva K Ellegård
Dec 6, 2005·Otolaryngologic Clinics of North America·Melissa McCarty Statham, Allen Seiden
Jan 30, 2015·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Aleksandra BaracValentina Arsic Arsenijevic
Oct 29, 2004·The Laryngoscope·Xavier DufourJean-Michel Klossek
Apr 3, 2003·The Laryngoscope·Pierre BonfilsPaul Avan
Oct 4, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A A S SenaS M Oliani
Jan 3, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G K ScaddingUNKNOWN British Society for Allergy and Clinical Immunology
Jan 31, 2012·International Forum of Allergy & Rhinology·Yogesh MorePeter Catalano
Dec 6, 2011·The Journal of Small Animal Practice·D E Holt, M H Goldschmidt
Aug 2, 2005·Immunology and Allergy Clinics of North America·P van CauwenbergeC Bachert
Apr 6, 2004·Immunology and Allergy Clinics of North America·Glenis K Scadding
Jul 24, 2015·DNA and Cell Biology·Sibel ÖzdaşHüseyin Dere
Nov 18, 2014·International Forum of Allergy & Rhinology·Sarfaraz M BanglawalaRodney J Schlosser
Apr 25, 2000·Acta Oto-laryngologica·L JohanssonM Bende
Aug 16, 2016·Acta otorrinolaringológica española·M Soledad Cabrera-RamírezÁngel Ramos-Macías
Oct 16, 2014·The Annals of Otology, Rhinology, and Laryngology·Aleksandar PerićCveta Spadijer-Mirković
May 2, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Ibrahim ErcanSuat Turgut
Jun 8, 2017·The Annals of Otology, Rhinology, and Laryngology·Cveta Špadijer MirkovićDanilo Vojvodić
Oct 8, 2008·Otolaryngologia polska. The Polish otolaryngology·Jurek Olszewski, Jarosław Miłoński
Feb 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Roee LandsbergDan M Fliss

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