Abstract
Abnormal glucose metabolism (AGM) is common but underestimated in patients with coronary heart disease (CHD). Here, we reported 898 in-hospital patients with primary hypertension (PH) at the university hospitals in developed regions of China. Oral glucose tolerance test (OGTT) was performed in those without known type-2 diabetes mellitus (2-DM). A total of 158 patients had known 2-DM and 32 were newly diagnosed as 2-DM by fasting blood glucose (FBG). OGTT revealed that 83 had 2-DM and 296 had impaired glucose tolerance (IGT). The proportion of 2-DM and AGM increased from 21.2 to 30.4% and from 57.5 to 68.7% upon OGTT. Prevalence of AGM and 2-DM increased with the increase of age, and incidence of AGM and 2-DM was significant higher in patients with risk factors (including CHD, overweight, hyperlipidaemia, proteinuria) than those without risk factors mentioned above. Glucose was not sufficiently controlled in 55.1% of the patients with 2-DM upon treatment, well controlled in 35.4% and not controlled in 9.5%. So AGM is also prevalent in PH patients especially the elders and those with risk factors, which was underestimated in most cases. Moreover, much lower awareness, treatment and control of 2-DM occurred in some regions of Chi...Continue Reading
References
Dec 1, 1987·Controlled Clinical Trials·J D NeatonJ A Cutler
Aug 11, 1993·JAMA : the Journal of the American Medical Association·J D NeatonR McDonald
Sep 11, 1998·BMJ : British Medical Journal
Jul 27, 1999·Circulation·S S FranklinD Levy
Apr 14, 2000·BMJ : British Medical Journal·R DonnellyA D Morris
Mar 10, 2001·Circulation·S S FranklinD Levy
Nov 25, 2003·Diabetes Care·Saul Genuth
Nov 4, 2004·European Heart Journal·Małgorzata BartnikUNKNOWN Euro Heart Survey Investigators
Dec 24, 2005·Stroke; a Journal of Cerebral Circulation·Dahlia Weitzman, Uri Goldbourt
Mar 28, 2006·The American Journal of Medicine·Juan García-PuigUNKNOWN AVANT Study Group Investigators
Sep 21, 2006·European Heart Journal·Da-Yi HuUNKNOWN China Heart Survey Group
May 5, 2007·Stroke; a Journal of Cerebral Circulation·Thomas JeerakathilSumit R Majumdar
May 29, 2007·Internal Medicine·Kazuo TakahashiShuhei Yamaguchi
Jun 15, 2007·Journal of Hypertension·Giuseppe ManciaUNKNOWN European Society of Cardiology
Jun 15, 2007·Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria·O E EssienC O Odigwe
Jul 17, 2007·The American Journal of Cardiology·Koon-Hou MakSuok-Kai Chew
Aug 9, 2007·Journal of the Cardiometabolic Syndrome·Lydia Sebba Souza MariosaMaria Teresa Zanella
Aug 21, 2007·JAMA : the Journal of the American Medical Association·Sean M DonahoeElliott M Antman
Citations
Jun 29, 2012·Clinical and Experimental Hypertension : CHE·Ping GuShisen Jiang
Mar 10, 2009·Diabetes/metabolism Research and Reviews·Yang-Xin ChenJing-Feng Wang
Jun 1, 2012·Clinical Biochemistry·Zhu-zhi WenJing-feng Wang