PMID: 5697334Jan 1, 1968Paper

Glucose-6-phosphate dehydrogenase deficiency in Chinese

Journal of Clinical Pathology
H C LaiK S Leung

Abstract

In a Chinese population 1,000 full-term male neonates and a further 117 jaundiced neonates of both sexes were studied in an investigation of the frequency of deficiency of erythrocyte glucose-6-phosphate dehydrogenase (G6PD). This enzyme was found to be deficient in 3.6% of male neonates. Correlation of the results with the birthplace of the 602 mothers who were known to come from Kwangtung province showed no significant differences in the frequency of the deficiency between certain parts of the province.The deficiency of G6PD in hemizygous males is profound but it is not associated with erythrocyte acid monophosphoesterase deficiency in Chinese in Hong Kong. The G6PD deficiency accounts for 15.4% of all the 117 cases of neonatal jaundice. The relative importance of G6PD deficiency as a cause of neonatal jaundice does not differ materially in male and female mutants. Neonatal jaundice can occur in all genotypes of G6PD mutation in Chinese.

References

Sep 1, 1961·American Journal of Diseases of Children·H N KIRKMAN, H D RILEY
Oct 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·S H BOYERR G WEILBACHER
Jul 11, 1964·British Medical Journal·T K CHANC C WONG

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Citations

May 29, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·J J Kaneko
Oct 1, 1979·British Journal of Haematology·W N GibbsM Lowry
Feb 24, 2009·Blood Cells, Molecules & Diseases·Ella T NkhomaErnest Beutler
Apr 12, 2014·Free Radical Research·H-Y HoD T-Y Chiu
May 29, 2016·Clinics in Perinatology·Anna D CunninghamDaria Mochly-Rosen
Sep 1, 1972·Journal of Medical Genetics·M T Tsuang, H S Tsuang
Feb 1, 1969·Postgraduate Medical Journal·T Valaes
Nov 6, 2009·American Journal of Physical Anthropology·Stuart A Altmann
Aug 1, 1971·The Journal of Pathology·C EdwardsJ Arias-Stella
Jun 1, 1972·The Journal of Pathology·C EdwardsP Harris
Jun 1, 1973·The Journal of Pathology·M S Dunnill, W Halley
Feb 1, 1977·The Journal of Pathology·M S McLachlanM J Fulker
Mar 17, 2007·Applied Microbiology and Biotechnology·Georg Sindelar, Volker F Wendisch

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