PMID: 9063Apr 1, 1976

Glucose 6-phosphate dehydrogenase in rainbow trout

Biochemical Genetics
S D Cederbaum, A Yoshida

Abstract

Electrophoretic analysis of glucose 6-phosphate dehydrogenase from liver and blood of rainbow trout revealed a complex series of bands, which could differ between fish. The partial interconvertible nature of these bands was demonstrated with enzyme that had been incompletely inactivated at pH 8.4. In a single population of 40 fish, a homozygote and a heterozygote for an electrophoretic variant allele were found. We suggest that G6PD in rainbow trout liver and blood is determinted by two alleles at a single locus, with posttranslational modification responsible for the complex electrophoretic patterns seen. The basis for this variation appears to be NADH binding to the protein molecule. Another variant and other properties of the enzyme are described.

References

Oct 15, 1972·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·J J Stegeman, E Goldberg
Apr 8, 1970·Biochemical and Biophysical Research Communications·A BonsignoreA De Flora
Apr 14, 1971·Biochimica Et Biophysica Acta·K Taketa, A Watanabe
Dec 1, 1971·Archives of Biochemistry and Biophysics·A BonsignoreA De Flora
Oct 15, 1971·Biochemical and Biophysical Research Communications·D Niethammer, F M Huennekens
Jun 18, 1971·Nature·T Uyeno, R R Miller
Dec 1, 1971·Biochemical Genetics·J J Stegeman, E Goldberg
Apr 1, 1967·The Journal of School Health·J L Schwartz, M Dubitzky
Jan 1, 1967·Annals of Human Genetics·H Grüneberg
Mar 1, 1969·European Journal of Biochemistry·P Cohen, M A Rosemeyer
Aug 26, 1966·Science·S OhnoE Beutler
May 1, 1967·Journal of Biochemistry·T Matsuda, Y Yugari
Nov 30, 1963·Nature·R A FILDES, C W PARR
Mar 1, 1965·Journal of Medical Genetics·E R HUEHNS, E M SHOOTER

Citations

Dec 24, 1997·Comparative Biochemistry and Physiology. Part A, Physiology·W J Poly
Jun 1, 1983·The Journal of Experimental Zoology·G M Kidder

Related Concepts

Metazoa
Electrophoresis, Starch Gel
Glucosephosphate Dehydrogenase
Guanine Nucleotides
Genetic Carriers
Alloenzymes
Liver
NADP
Salvelinus
Variation (Genetics)

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