Glucose challenge test threshold values in screening for gestational diabetes among black women

American Journal of Obstetrics and Gynecology
Sarah FriedmanOvadia Abulafia

Abstract

The objective of the study was to assess the incidence of gestational diabetes among black women according to various cut-off values of the glucose challenge test. We performed a retrospective chart review of black patients who had a 50-g, 1-hour glucose challenge test between 24 and 28 weeks' gestation of 130 mg/dL or higher followed by a 100-g, 3-hour glucose tolerance test. Results were categorized in 10-mg/dL increments. Gestational diabetes was diagnosed by 2 or more abnormal values using the Carpenter-Coustan criteria. The study included 387 patients. The incidence of gestational diabetes diagnosed overall in all patients with a glucose challenge test of 130 mg/dL or higher was 31.2%. The incidence of gestational diabetes in individuals with a challenge test in the range of 130 to 140 mg/dL was 10.7%. The incidence of gestational diabetes with a screening test of 180 mg/dL or higher was 72.0%. Our data support the use of 130 mg/dL as the threshold for a positive glucose challenge test and suggest the use of a glucose tolerance test to confirm the diagnosis of gestational diabetes for screening values up to 200 mg/dL.

References

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Citations

Jan 23, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·L A TemmingA G Cahill
Mar 8, 2011·The Journal of Obstetrics and Gynaecology Research·Samira Behboudi GandevaniShiva Dibaj
Mar 20, 2020·Archives of Gynecology and Obstetrics·Sivan Zuarez-EastonRaed Salim
Jun 26, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Eyal RomRaed Salim

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