PMID: 4290984Aug 1, 1966Paper

Glucose metabolism in the mucosa of the small intestine. Glycolysis in subcellular preparations from the cat and rat

The Biochemical Journal
L M Srivastava, G Hübscher

Abstract

1. Lactic acid formation in supernatant fractions of homogenates of cat or rat small-intestinal mucosa was measured under optimum conditions with glucose, fructose, glucose 6-phosphate, fructose 1,6-diphosphate or 3-phosphoglycerate as substrate. 2. Between 80 and 107% of the glycolytic activity of the homogenate was recovered in these particle-free preparations when glucose, fructose, glucose 6-phosphate or fructose 1,6-diphosphate was used as substrate. 3. Evidence was obtained that hexokinase and phosphofructokinase were the rate-limiting enzymes in the initial sequence of glycolytic reactions. The limitation of rate by hexokinase was much more pronounced in preparations from the cat than in those from the rat. 4. With subcellular preparations from cat or rat small intestine lactic acid was also formed from ribose 5-phosphate and at rates similar to those observed with glucose. 5. A higher rate of glycolysis was observed with glucose 6-phosphate as substrate with preparations from the proximal half of the small intestine of the rat as compared with the distal half. 6. Mucosal preparations from rats starved for 24-48hr. exhibited only about one-quarter of the glycolytic activity of those of fed control groups. The decreased r...Continue Reading

Citations

Dec 3, 1967·Nature·J C DoeryG C De Gruchy
Jul 1, 1984·Pflügers Archiv : European journal of physiology·J Hamar, G Hutiray
Sep 15, 1971·FEBS Letters·W C. Hülsmann
Jan 12, 1971·FEBS Letters·J W.O. van den Berg, W C. Hülsmann
Jan 1, 1981·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·C BodeJ C Bode
Jul 24, 1978·Research in Experimental Medicine. Zeitschrift Für Die Gesamte Experimentelle Medizin Einschliesslich Experimenteller Chirurgie·H Menge, J W Robinson
Apr 2, 2010·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Sergio PolakofJosé L Soengas
Nov 2, 2013·American Journal of Physiology. Gastrointestinal and Liver Physiology·Phuntila TharabenjasinRonaldo P Ferraris
Jan 1, 1972·Acta Medica Scandinavica. Supplementum·R H HermanY F Herman
Jul 1, 1969·Zeitschrift für Ernährungswissenschaft·E Scharrer, H Zucker
Nov 14, 1997·The American Journal of Physiology·S E FlemingM D Fitch
Mar 1, 1978·The American Journal of Physiology·Y F ShiauJ B Weiss
Jul 1, 1972·Biochemical Pharmacology·J D Teale, A H Love
May 9, 1972·Biochimica Et Biophysica Acta·M GraceyA Oshin
May 28, 1973·Biochimica Et Biophysica Acta·G M Jones, R J Mayer
Oct 25, 1972·Biochimica Et Biophysica Acta·H Nakayama, E Weser
Jan 1, 1988·The International Journal of Biochemistry·A O Abuelgassim, S M Khoja
Jan 8, 1991·Biochimica Et Biophysica Acta·S M KhojaA M Salem
Nov 1, 1974·Comparative Biochemistry and Physiology. A, Comparative Physiology·D R Romsos, G A Leveille
May 1, 1975·Comparative Biochemistry and Physiology. A, Comparative Physiology·A L Luisier, J W Robinson
Aug 1, 1968·Experimental and Molecular Pathology·G RagnottiA Bernelli-Zazzera
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Antonio J VillatoroRick Visser

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