PMID: 9187986Jun 1, 1997Paper

Glucose versus lactated Ringer's solution during pediatric cardiac surgery

Journal of Cardiothoracic and Vascular Anesthesia
A AouifiJ J Lehot

Abstract

Whether intraoperative fluid infusion should contain glucose during pediatric cardiac surgery remains controversial. This study was performed to compare the effects of glucose and glucose-free solutions on blood glucose and blood insulin levels during total repair of congenital heart diseases. Prospective randomized and blinded study. Cardiovascular university center. Forty nondiabetic children, weight ranging from 4 to 10 kg, scheduled for cardiac surgical procedures requiring cardiopulmonary bypass (CPB) without total circulatory arrest. Group R (n = 20) was administered lactated Ringer's solution intraoperatively, and group G (n = 20) received 5% glucose. Fluids were infused at a rate of 3 mL/kg/h in the two groups from the induction of anesthesia to the end of the surgical procedure. Blood glucose and insulin were sampled before infusion (Tzero), before CPB (T1), 10 minutes after initiation of CPB (T2), 10 minutes after initiation of rewarming (T2), and at the end of the procedures (T4). Postoperatively, blood glucose was measured at the first, 12th, and 24th hours. During the prabypass period, three children in group R had severe hypoglycemia (blood glucose < 40 mg/dL). After initiation of CPB, blood glucose increased in b...Continue Reading

References

Mar 1, 1992·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K R WagnerR E Myers
Jan 1, 1992·Critical Care Medicine·F E Sieber, R J Traystman
Apr 1, 1991·Anesthesia and Analgesia·S Metz, A S Keats
Jun 1, 1990·Stroke; a Journal of Cerebral Circulation·D J CombsC Smith
Jul 1, 1986·Stroke; a Journal of Cerebral Circulation·R N Auer
Jan 1, 1985·British Journal of Anaesthesia·B K Siesjö, T Wieloch
Dec 12, 1968·The New England Journal of Medicine·D BaumD Porte
Jul 1, 1983·The American Journal of Cardiology·G BenzingM A Sperling
Sep 1, 1984·Anaesthesia·K Payne, P Ireland
May 1, 1994·The Journal of Clinical Endocrinology and Metabolism·D J Kennedy, J F Butterworth

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Citations

Jan 16, 2002·The Annals of Thoracic Surgery·E R Stephenson, J L Myers
Mar 29, 2002·Neurochemistry International·Avital Schurr
Jan 28, 2010·The Annals of Thoracic Surgery·William M DeCampliDonald E Felix

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