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GluN2B-containing NMDA receptors contribute to the beneficial effects of hydrogen sulfide on cognitive and synaptic plasticity deficits in APP/PS1 transgenic mice

Neuroscience

Sep 2, 2016

Yuan-Jian YangBo Wei

Abstract

Alzheimer's disease (AD) is the most common type of clinical dementia. Previous studies have demonstrated that hydrogen sulfide (H2S) is implicated with the pathology of AD, and exogenous H2S attenuates spatial memory impairments in AD animal models. However, the molecular mechanism by ...read more

Mentioned in this Paper

Spatial Memory
Study
GRIN2B
Sulfides
Presenilin-1
Presenilin 1, mouse
Antagonist Muscle Action
Amyloid Beta Precursor Protein Measurement
Action Potentials
Sodium bisulfide
1
1
27
Paper Details
References

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GluN2B-containing NMDA receptors contribute to the beneficial effects of hydrogen sulfide on cognitive and synaptic plasticity deficits in APP/PS1 transgenic mice

Neuroscience

Sep 2, 2016

Yuan-Jian YangBo Wei

PMID: 27581687

DOI: 10.1016/j.neuroscience.2016.08.033

Abstract

Alzheimer's disease (AD) is the most common type of clinical dementia. Previous studies have demonstrated that hydrogen sulfide (H2S) is implicated with the pathology of AD, and exogenous H2S attenuates spatial memory impairments in AD animal models. However, the molecular mechanism by ...read more

Mentioned in this Paper

Spatial Memory
Study
GRIN2B
Sulfides
Presenilin-1
Presenilin 1, mouse
Antagonist Muscle Action
Amyloid Beta Precursor Protein Measurement
Action Potentials
Sodium bisulfide
1
1
27

Similar Papers Found In These Feeds

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Paper Details
References
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