PMID: 7522676Jun 1, 1994Paper

Glutamate receptor update

Current Opinion in Neurobiology
G L Westbrook

Abstract

The past year has seen significant advances in matching the actions of recombinant glutamate receptors with the actions of native receptors, and in mapping their distribution and regulation. The discovery of a novel RNA editing mechanism for AMPA receptors and a revised view of the transmembrane topology of the NMDA receptor subunit, NR1, are particularly noteworthy. Seven metabotropic glutamate receptor subtypes have been identified with several interesting expression patterns and transduction mechanisms; results from work on these subtypes has led to a provocative model of the ligand-binding site. Functional studies of metabotropic receptors have been enhanced by the development of the first subtype-specific antagonist.

References

Jun 30, 1992·Biochemical and Biophysical Research Communications·H SugiharaS Nakanishi
Nov 27, 1992·Science·J D ClementsG L Westbrook
Jul 2, 1992·Nature·T KutsuwadaM Arakawa
Oct 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·G M DurandR S Zukin
Dec 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·J LermaB Mellström
Oct 14, 1994·European Journal of Pharmacology·J C Marvizón, M Baudry
Jan 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·J Egebjerg, S F Heinemann
Jan 1, 1993·Trends in Pharmacological Sciences·D D Schoepp, P J Conn
Mar 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·D P YounkinD Pleasure
May 1, 1993·Neuron·C Rosenmund, G L Westbrook
Jun 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·R Planells-CasesM Montal
Aug 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·T A BenkeK J Angelides
Oct 29, 1993·Science·C RosenmundG L Westbrook
Jul 1, 1994·Physiological Reviews·C J McBain, M L Mayer
Apr 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·N Kato

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Citations

Jun 19, 2004·Archives of Pharmacal Research·Sunoh Kim, Hyewhon Rhim
Jul 2, 2003·Neurotoxicity Research·Thomas N ChaseJustin D Oh
May 1, 1997·Journal of Neurology·P J Shaw, P G Ince
Dec 30, 1996·European Journal of Pharmacology·L Giménez-LlortE Martínez
Apr 12, 2003·Neurochemistry International·Linda K FriedmanJana Velísková
May 19, 2001·Neurologic Clinics·I NajmD Janigro
Jul 27, 2001·Journal of Chemical Neuroanatomy·Y SmithA I Levey
Jun 1, 1996·Current Opinion in Neurobiology·D S McGehee, L W Role
Aug 1, 2002·Behavioral Neuroscience·Jerry W RudyRandall C O'Reilly
Feb 25, 2005·Behavioral Neuroscience·Staci D BilboSteven F Maier
Sep 30, 1998·The European Journal of Neuroscience·C LabrakakisH Kettenmann
Jul 15, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J C HsuJ H Eubanks
Jun 1, 1995·The European Journal of Neuroscience·T R TölleW Zieglgänsberger
Nov 1, 1996·The European Journal of Neuroscience·J M García-Barcina, C Matute
Oct 10, 2003·Journal of Neurophysiology·Patrick S Mangan, Jaideep Kapur
Oct 25, 2001·Proceedings of the National Academy of Sciences of the United States of America·B S LiH C Pant
May 16, 1998·Brain Research. Molecular Brain Research·J Q Wang, J F McGinty
Mar 11, 2016·The Journal of Toxicological Sciences·Kanae UmedaShigeru Ohta
Apr 17, 2007·The European Journal of Neuroscience·Yukio Akaneya
Oct 14, 2009·The Journal of Physiology·Kresimir Krnjević
Oct 23, 1997·The Journal of Comparative Neurology·J CalderóJ E Esquerda

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