PMID: 3709116Jan 1, 1986Paper

Glutathione in the red blood cells of embryonic mice

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
T Brittain, B Tottle

Abstract

A micro-method for the determination of red blood cell glutathione levels has been developed. It has been shown that, in order to obtain true values of glutathione concentrations within red blood cells, it is necessary to correct for loss of labelled glutathione and also to take account of the time taken to complete the analytical procedure. Glutathione is the major small molecular weight thiol present in embryonic red blood cells. The glutathione to haemoglobin ratio is maintained at 0.6 from 13 days gestation to adulthood in the mouse. Decay of glutathione in both adult and embryonic red blood cells can be avoided by incubation of the red blood cells in glucose containing buffers.

References

Jan 1, 1979·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·C J Yu, N S Agar
Mar 1, 1966·Analytical Biochemistry·V H Cohn, J Lyle
Jan 1, 1983·Comparative Biochemistry and Physiology. A, Comparative Physiology·R M Wells, T Brittain
Jan 1, 1983·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·K L RahejaC Cho

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