Glutathione S-transferase and aluminum toxicity in maize

Functional Plant Biology : FPB
Geraldo M A CançadoMarcelo Menossi

Abstract

Aluminum (Al) toxicity induces changes in the expression of several genes, some of which are involved in plant responses to oxidative stress. Using mRNA differential display, we identified a maize Al-inducible cDNA encoding a glutathione S-transferase (GST). The gene was named GST27.2 owing to its homology to the maize gene GST27, which is known to be induced by xenobiotics. GST27.2 is present in the maize genome as a single copy and analysis of its expression pattern revealed that the gene is expressed mainly in the root tip. Expression was up-regulated in response to various Al and Cd concentrations in both Al-tolerant and Al-sensitive maize lines. Consistent with its role in plants, phylogenetic analysis of theta-type GSTs revealed that GST27.2 belongs to a group of proteins that respond to different stresses. Finally, structural analysis of the polypeptide chain indicates that the two amino acids that differ between GST27.2 and GST27 (E102K and P123L) could be responsible for alterations in activity and / or specificity. Together, these results suggest that GST27.2 may play an important part in plant defenses against Al toxicity.

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Citations

Jan 10, 2017·Frontiers in Plant Science·Alexey A DmitrievNataliya V Melnikova
Jan 23, 2020·Scientific Reports·Karl-Gustav RuggebergMaryann C Gruda
Apr 10, 2017·Plant Cell Reports·Irini Nianiou-ObeidatNikolaos E Labrou
Nov 10, 2017·Planta·Edith Alarcón-PobleteMarjorie Reyes-Díaz
Apr 11, 2008·The New Phytologist·Lyza G MaronLeon V Kochian
Jun 1, 2007·Functional Plant Biology : FPB·Rui A Gomes-JuniorRicardo A Azevedo
May 11, 2020·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Piriyaporn ThiendedsakulPhitsanu Tulayakul
Sep 11, 2010·BMC Plant Biology·Lucia MattielloMarcelo Menossi
Oct 6, 2021·Scientific Reports·Vitor Batista PintoJosé Marcelo Soriano Viana

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Datasets Mentioned

BETA
U12679

Methods Mentioned

BETA
transgenic
X-ray

Software Mentioned

GROMACS
MODELLER
BLAST
PRODRG
PROCHECK
MEGA
Clustal X

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