Glycated albumin level during late pregnancy as a predictive factor for neonatal outcomes of women with diabetes.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Daisuke SugawaraAtsuko Kawano

Abstract

To investigate the association between glycated albumin (GA) in diabetic mothers and complications in their children, and to determine GA cutoff values for predicting complications in infants. This hospital-based case-control study involved 71 Japanese diabetic mothers and their children. Mean GA values were compared between mothers of infants with and without complications, and relationship with number of complications was analyzed by Pearson's correlation. Receiver operating characteristic analysis determined GA cutoff values for complications in infants. GA was significantly higher in mothers of children with neonatal hypoglycemia (15.8 ± 3.2 versus 12.6 ± 1.2%, p <.001), respiratory disorders (15.7 ± 3.6 versus 12.9 ± 1.9%, p <.001), hypocalcemia (15.9 ± 3.7 versus 13.1 ± 1.8%, p <.001), polycythemia (15.7 ± 2.3 versus 13.8 ± 2.1%, p =.009), myocardial hypertrophy (16.1 ± 3.7 versus 13.1 ± 2.3%, p <.001), and large-for-date status (15.8 ± 2.4 versus 13.7 ± 3.1%, p = .006), showing significant positive correlation with number of complications in infants (r = .704, 95%CI: 0.579-0.797, p < .001). Cut-off values were within the limits of 13.6-14.7%. GA is useful for predicting pregnancy outcomes in mothers with diabetes and mus...Continue Reading

References

Apr 8, 1998·Archives of Pediatrics & Adolescent Medicine·L CorderoS G Gabbe
Apr 17, 2007·Diabetes Research and Clinical Practice·Yumi MiyashitaNaoko Tajima
Jul 18, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·Y W Cheng, A B Caughey
Feb 27, 2009·Diabetes Research and Clinical Practice·M KogaS Kasayama
Mar 2, 2010·Diabetes Care·UNKNOWN International Association of Diabetes and Pregnancy Study Groups Consensus PanelMaria Ines Schmidt
Jun 16, 2010·Annals of Internal Medicine·David C ZiemerLawrence S Phillips
Aug 21, 2010·Endocrine Journal·Masafumi Koga, Soji Kasayama
Oct 23, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Masafumi KogaSoji Kasayama
Jan 10, 2012·Journal of Diabetes Science and Technology·Takuji KohzumaBarry I Freedman
Jan 10, 2012·Journal of Diabetes Science and Technology·Randie R Little
Aug 10, 2012·Diabetes Care·Stephen P JuraschekElizabeth Selvin
Mar 26, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Jiemin PanWeiping Jia
Apr 26, 2013·The Journal of Medical Investigation : JMI·Masafumi KogaUNKNOWN Japan Diabetes Society's Committee Of Research On Type 1 Diabetes Mellitus
Mar 19, 2014·Clinica Chimica Acta; International Journal of Clinical Chemistry·Masafumi Koga
Apr 1, 2014·Endocrine Journal·Kaori InoueMitsuhiko Noda
Oct 19, 2010·Journal of Diabetes Investigation·Yutaka SeinoKohjiro Ueki
Dec 17, 2015·Experimental and Therapeutic Medicine·Yaping HuangGuangyong Ye

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Citations

Apr 23, 2019·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Neuza MendesFátima Serrano
Jul 16, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Xiaoming ZhangHuixia Yang
Jun 27, 2019·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Neuza MendesFátima Serrano
Nov 18, 2019·Clinica Chimica Acta; International Journal of Clinical Chemistry·Mustapha Zendjabil
Jul 27, 2021·Clinica Chimica Acta; International Journal of Clinical Chemistry·Shin AleksKabytaev Kuanysh

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