Glycoconjugates for glucose transporter-mediated cancer-specific targeting and treatment.

Carbohydrate Research
Junjie FuJian Yin

Abstract

First observed in 1920s, the Warburg effects have inspired scientists to harness the unique glucose metabolism of cancer cells for targeted therapy for a century. Carbohydrate-drug conjugates are explicitly designed for selective uptake by cancer cells overexpressing glucose transporters. We summarize the progress in developing glycoconjugates for cancer-specific targeting and treatment over the past decade (2010-2020) and point to some future directions in this field.

Citations

Feb 13, 2021·International Journal of Molecular Sciences·Marta WoźniakSiddarth Agrawal
May 1, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marta WoźniakSiddarth Agrawal
May 3, 2021·European Journal of Medicinal Chemistry·Meizhu WangWen Zhou
Aug 28, 2021·Cancers·Monika Pliszka, Leszek Szablewski

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