Glycoconjugates of the lateral prostate of the guinea pig: a lectin histochemical study

The Prostate
L Chan, Y C Wong

Abstract

The present study examined the glycoconjugates of the lateral prostate using a battery of lectins. The results indicated that the secretory epithelium was rich in mannose (Man), N-acetylglucosamine (GlcNAc), galactose (Gal), N-acetylgalactosamine (GalNAc), and complex oligosaccharides. Con A (concanavalin A), LCA (Lens culinaris agglutinin), PSA (Pisum sativum agglutinin), WGA (wheat germ agglutinin), PWM (pokeweed mitogen), RCA-I (Racinus communis isolectin I), and PHA-P (Phaseolus vulgaris agglutinin-P) reacted intensely with both epithelia and stroma, while SBA (soybean agglutinin) and PNA (peanut agglutinin), which bind to terminal Gal, GalNAc, and Gal beta 1,3 GalNAc appeared to be specific to the secretory epithelium. SBA and PNA were useful as markers in the study of the secretory function of the prostate gland. The present study has shown that the Golgi apparatus of prostatic epithelial cells was rich in fucose (Fuc), oligomers of GlcNAc, Gal beta 1,3 GalNAc, Gal, and Man containing glycoconjugates, indicating that the gland was actively involved in glycosylation. The present study has also shown that LTA (Lotus tetragonolobus agglutinin) is a good marker for the epithelial Golgi. PNA also bound to the epithelial baseme...Continue Reading

References

Aug 15, 1978·European Journal of Biochemistry·W HeynsP De Moor
Nov 1, 1989·The Histochemical Journal·C HaukeF Sinowatz
Jan 1, 1987·Annual Review of Biochemistry·C B Hirschberg, M D Snider
Jan 1, 1986·Annual Review of Biochemistry·H Lis, N Sharon
Jan 1, 1985·Annual Review of Biochemistry·R Kornfeld, S Kornfeld
May 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·B A Schulte, S S Spicer
Apr 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·G R GuntherG M Edelman
Jan 1, 1974·International Review of Cytology·G L Nicolson
Jan 1, 1970·Histochemie. Histochemistry. Histochimie·H PuchtlerH M Conner
Aug 1, 1983·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·J Roth
Mar 1, 1984·The Histochemical Journal·A Tsukise, K Yamada
Jan 1, 1980·Advances in Carbohydrate Chemistry and Biochemistry·J Montreuil
Feb 1, 1982·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M Hsu, L Raine
May 14, 1982·Biochemical and Biophysical Research Communications·T T Glant
Mar 1, 1981·Canadian Journal of Biochemistry·R K Chopra, J M Bowness
Jan 1, 1956·The Journal of Pathology and Bacteriology·D BRANDES, G H BOURNE
Feb 1, 1964·British Journal of Pharmacology and Chemotherapy·E W HORTON, C J THOMPSON
Apr 1, 1964·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·L PARKINR J MADDEN
Mar 1, 1961·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·G QUINTARELLIW PIGMAN

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