Total glycosylated haemoglobin (HbA1) levels were measured in 94 diabetic children aged between 3 and 19 years. The results were compared with traditional methods of assessing blood glucose control. HbA1 levels correlated with home urine glucose testing (P less than 0.05), with 24-hour urine glucose excretion (P less than 0.01), and with height velocity (P less than 0.001). Within the first two of these parameters there was a wide scatter of results, suggesting the inaccuracy of these methods for assessing control. The association of raised HbA1 levels with height velocities less than 10th centile shows the effect of poor control on growth. HbA1 may prove to be an objective method for assessing long-term blood glucose levels in diabetes, and thus it may be possible to determine the effect of good control in the prevention of the various diabetic complications.
Comparison between the plasma insulin and glucose responses to five different insulin regimes in diabetic patients
Haemoglobin A1c, home urine sugar testing and serum cholesterol and HDL-cholesterol in diabetic children
Relationship between insulin injection regimen and metabolic control in young Danish type 1 diabetic patients. The Danish Study Group of Diabetes in Childhood
Glycosylated haemoglobin and glycosylated albumin: evaluation of different methods in diabetic control
Improved metabolic outcome in a Danish diabetic paediatric population aged 0-18 yr: results from a nationwide continuous Registration
Glycaemic control and microvascular complication among patients with youth onset diabetes in India using differing types of insulin and methods of glucose monitoring
A nation-wide cross-sectional study of glycosylated haemoglobin in Danish children with type 1 diabetes
Nutrition and somatomedin. XIV. Altered levels of somatomedins and somatomedin inhibitors in rats with streptozotocin-induced diabetes
Autoimmune Diabetes & Tolerance
Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.