PMID: 15334337Jan 1, 1986Paper

Glycosylated hemoglobin in dogs: precision, stability, and diagnostic utility

Veterinary Clinical Pathology
J R Easley

Abstract

The precision and stability of the ion exchange chromatography assay for canine glycosylated hemoglobin (HbA(1)) were examined. The coefficient of variation (CV) of within-run replicate assays was 1.3 to 2.6%; the CV of between-run duplicate assays was 3.1%. The mean HbA(1) content in 44 healthy dogs was 7.1% (SD = 1.1%, range = 5.1-9.7%). Paired aliquots of 12 blood samples were stored at 4 degrees C and 25 degrees C, and HbA(1) was measured on the day of collection and at 3, 5, and 7 days after collection. In the blood stored at 4 degrees C, no significant increase in the HbA(1) content was seen. No significant increase in HbA(1) content was found in the blood stored at 25 degrees C after 3 days, but dramatic increases were observed after 5 and 7 days of storage. No significant difference was observed in the HbA1 content in heart blood collected 18 hours after death from 9 dogs kept at 25 degrees C. The HbA(1) content was measured in 10 hospitalized diabetic dogs. Five of the dogs had received no insulin and all 5 had elevated HbA(1) values. The other 5 dogs had received insulin for 1 to 9 months; 2 of the 5 had increased HbA(1) content. The HbA(1) content was determined periodically for 9 months in one diabetic dog and it de...Continue Reading

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Citations

Jul 25, 2000·The Journal of Small Animal Practice·M C Marca, A Loste
Dec 20, 2002·The Journal of Small Animal Practice·L J DavisonB Catchpole
Apr 8, 2017·Veterinary Clinical Pathology·Anne F GoemansIan K Ramsey
Dec 12, 2007·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·F K MohammadO A H Ahmed
Aug 8, 2007·Journal of Veterinary Science·M H Al-Zubaidy, F K Mohammad
Dec 1, 1990·Clinical Otolaryngology and Allied Sciences·P N Carding, G E Murty
Feb 27, 2020·American Journal of Veterinary Research·Francesca Del BaldoFederico Fracassi

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