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Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan

The Journal of Cell Biology

Feb 28, 1998

T P SkeltonIvan Stamenkovic

PMID: 9442118

Abstract

Glycosylation has been implicated in the regulation of CD44-mediated cell binding of hyaluronan (HA). However, neither the relative contribution of N- and O-linked glycans nor the oligosaccharide structures that alter CD44 affinity for HA have been elucidated. To determine the effect of...read more

Mentioned in this Paper

Metabolic Process, Cellular
Flow Cytometry
Oligosaccharide Biosynthetic Process
Immunoglobulin Activity
Glycosidase Activity
Electrophoresis, Capillary
Somatostatin-Secreting Cells
Chinese Hamster Ovary Cell
Surface Properties
CD44
68
Paper Details
References
  • References40
  • Citations97
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  • References40
  • Citations97
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Glycosylation provides both stimulatory and inhibitory effects on cell surface and soluble CD44 binding to hyaluronan

The Journal of Cell Biology

Feb 28, 1998

T P SkeltonIvan Stamenkovic

PMID: 9442118

DOI:

Abstract

Glycosylation has been implicated in the regulation of CD44-mediated cell binding of hyaluronan (HA). However, neither the relative contribution of N- and O-linked glycans nor the oligosaccharide structures that alter CD44 affinity for HA have been elucidated. To determine the effect of...read more

Mentioned in this Paper

Metabolic Process, Cellular
Flow Cytometry
Oligosaccharide Biosynthetic Process
Immunoglobulin Activity
Glycosidase Activity
Electrophoresis, Capillary
Somatostatin-Secreting Cells
Chinese Hamster Ovary Cell
Surface Properties
CD44
68

Feeds With Similar Papers

Adhesion Molecules in Health and Disease

Cell adhesion molecules are a subset of cell adhesion proteins located on the cell surface involved in binding with other cells or with the extracellular matrix in the process called cell adhesion. In essence, cell adhesion molecules help cells stick to each other and to their surroundings. Cell adhesion is a crucial component in maintaining tissue structure and function. Discover the latest research on adhesion molecule and their role in health and disease here.

Related Papers

The Journal of Cell Biology

Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan

The Journal of Cell BiologyMarch 1, 1996
A BartolazziIvan Stamenkovic
Paper Details
References
  • References40
  • Citations97
1234
  • References40
  • Citations97
12345...

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