GM-CSF at relatively high topic concentrations can significantly enhance the healing of surgically induced chronic wounds after radiotherapy

Medical Oncology
J O FernbergG Masucci

Abstract

Combinations of radiotherapy and surgery are often used in local cancer treatments. Preoperative radiotherapy may delay wound healing after surgery. Chronic wounds are debilitating conditions that require frequent medical attention. Two patients suffering from chronic and slowly healing wounds post-surgery and preoperative radiotherapy are described. A significant acceleration of the healing by local injections with GM-CSF was demonstrated.

Citations

Jan 9, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Stephan BarrientosMarjana Tomic-Canic
Jun 20, 2006·Free Radical Biology & Medicine·Reto AsmisLars M Asmis
Sep 9, 2017·PloS One·Kazutoshi FujitaMasao Kakibuchi
Feb 25, 2003·American Journal of Physiology. Lung Cellular and Molecular Physiology·Ryan P CharbeneauBethany B Moore
Sep 15, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Reto AsmisJohn J Mieyal

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