Goblet cell density and distribution in cats with clinically and histologically normal conjunctiva

Veterinary Ophthalmology
Lionel SebbagDavid J Maggs

Abstract

The aim of this study was to evaluate goblet cell density (GCD) and distribution in cats without clinical evidence of ocular surface disease and without histologic evidence of conjunctival disease. Fourteen Domestic Shorthair cats euthanized for reasons unrelated to this study. Before euthanasia, cats were verified using slit-lamp biomicroscopy and fluorescein staining to be free of eyelid or ocular surface abnormalities. Immediately after euthanasia, bilateral conjunctival specimens including third eyelid (TEL) were collected, routinely processed, and stained with periodic acid-Schiff and hematoxylin and eosin. Thirteen conjunctival regions were identified. For each region, GCD was expressed as the percentage of goblet cells/200 basal epithelial cells. Mean GCD ranged widely by region: anterior surface of the TEL = 48.8%, fornicial regions = 47.0%, palpebral regions = 38.5%, bulbar regions = 19.6%, and posterior surface of the TEL = 12.6%. The anterior surface of the TEL had significantly higher GCD than did the bulbar and the palpebral regions, but not the fornicial regions. Bulbar conjunctiva had significantly lower GCD than did all other conjunctival regions except the posterior surface of the TEL. No significant difference...Continue Reading

References

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Citations

Oct 22, 2016·Journal of Feline Medicine and Surgery·Réka EördöghBarbara Nell
Dec 19, 2018·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Jill C CovertDavid J Maggs
Apr 3, 2019·Veterinary Ophthalmology·Rosélia L S AraújoPaula D Galera
Jan 11, 2018·JFMS Open Reports·Lionel SebbagDavid J Maggs
Dec 20, 2020·Anatomia, histologia, embryologia·Débora de Oliveira GarciaCristiane Dos Santos Honsho
Jan 6, 2021·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Jessica WelssFriedrich Paulsen

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