Going Back to Kahlbaum's Psychomotor (and GABAergic) Origins: Is Catatonia More Than Just a Motor and Dopaminergic Syndrome?

Schizophrenia Bulletin
Dusan HirjakGeorg Northoff

Abstract

In 1874, Karl Kahlbaum described catatonia as an independent syndrome characterized by motor, affective, and behavioral anomalies. In the following years, various catatonia concepts were established with all sharing the prime focus on motor and behavioral symptoms while largely neglecting affective changes. In 21st century, catatonia is a well-characterized clinical syndrome. Yet, its neurobiological origin is still not clear because methodological shortcomings of hitherto studies had hampered this challenging effort. To fully capture the clinical picture of catatonia as emphasized by Karl Kahlbaum, 2 decades ago a new catatonia scale was developed (Northoff Catatonia Rating Scale [NCRS]). Since then, studies have used NCRS to allow for a more mechanistic insight of catatonia. Here, we undertook a systematic review searching for neuroimaging studies using motor/behavioral catatonia rating scales/criteria and NCRS published up to March 31, 2019. We included 19 neuroimaging studies. Studies using motor/behavioral catatonia rating scales/criteria depict cortical and subcortical motor regions mediated by dopamine as neuronal and biochemical substrates of catatonia. In contrast, studies relying on NCRS found rather aberrant higher-o...Continue Reading

References

Oct 1, 1977·Archives of General Psychiatry·M A Taylor, R Abrams
Dec 1, 1992·Psychiatry Research·D EbertW Kaschka
Jan 1, 1991·The Journal of Neuropsychiatry and Clinical Neurosciences·D Rogers
Mar 1, 1991·The British Journal of Psychiatry : the Journal of Mental Science·C E LundP J McKenna
Mar 1, 1991·The British Journal of Psychiatry : the Journal of Mental Science·P J McKennaC A Biggins
Apr 1, 1991·Biological Psychiatry·J A Wilcox
Sep 1, 1990·British Journal of Obstetrics and Gynaecology·J KleijnenP Knipschild
Oct 1, 1988·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·N Herrmann, S J Lieff
Mar 1, 1985·The American Journal of Psychiatry·A B JosephD H O'Leary
Jan 1, 1974·Journal of Psychiatric Research·L R Gjessing
Oct 1, 1982·Archives of General Psychiatry·J R Stevens
Apr 1, 1994·Acta Psychiatrica Scandinavica·G S UngvariJ Lau
Dec 1, 1993·Psychiatry Research·K SatohR Morita
Dec 1, 1993·The Japanese Journal of Psychiatry and Neurology·K SatohY Yonekura
Jan 1, 1993·Neuropsychobiology·J A Wilcox
Mar 1, 1996·Journal of Neurology, Neurosurgery, and Psychiatry·S E StarksteinR Leiguarda
Mar 15, 1996·Biological Psychiatry·G NorthoffB Pflug
Feb 1, 1996·Acta Psychiatrica Scandinavica·G BushA Francis
Feb 1, 1996·Acta Psychiatrica Scandinavica·G BushA Francis
Aug 1, 1996·Journal of Clinical Psychopharmacology·P I Rosebush, M F Mazurek
Nov 1, 1995·Psychopharmacology·G NorthoffB Pflug
May 29, 1999·Movement Disorders : Official Journal of the Movement Disorder Society·G NorthoffB Bogerts
Jul 23, 1999·Annals of the New York Academy of Sciences·J N Joyce, E V Gurevich
Sep 25, 1999·Psychiatry Research·G NorthoffB Bogerts
Oct 3, 1999·Journal of Clinical Psychopharmacology·G NorthoffB Bogerts
Oct 3, 1999·Schizophrenia Research·B Baumann, B Bogerts
Mar 31, 2000·Comprehensive Psychiatry·P BräunigI Börner
May 10, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·V Di LazzaroJ C Rothwell
Dec 29, 2000·Journal of the American Academy of Child and Adolescent Psychiatry·N Ahuja
Feb 22, 2001·Journal of Psychosomatic Research·R EscobarC P Herrera
Mar 7, 2001·Pharmacopsychiatry·M Deuschle, F Lederbogen
May 30, 2001·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·F M Benes, S Berretta
Jan 5, 2002·Journal of Clinical Psychopharmacology·K T Graham, B T Carroll
Jan 5, 2002·European Archives of Psychiatry and Clinical Neuroscience·M Fink, M A Taylor
Dec 24, 2002·Journal of Cognitive Neuroscience·Kevin N OchsnerJohn D E Gabrieli
Jun 18, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·X De TiégeS Goldman
Sep 10, 2003·The Behavioral and Brain Sciences·Georg Northoff
May 12, 2004·Brain and Cognition·Edmund T Rolls
Oct 16, 2004·Psychological Review·Andrew K Moskowitz

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Citations

Feb 19, 2020·International Review of Psychiatry·Charles Mormando, Andrew Francis
May 6, 2020·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Jakob WasserthalDusan Hirjak
Jun 17, 2020·Psychological Medicine·Alexandre HarocheAli Amad
Oct 28, 2019·Schizophrenia Bulletin·Dusan HirjakGeorg Northoff

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Catatonia is a psychomotor syndrome with motor and behavioral symptoms, and can occur in both patients with or without psychiatric illness. Discover the latest research on Catatonia here.

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